Vergleich zwischen GE- und SE-Sequenzen in der MRT nach i.v. Applikation von superparamagnetischen Eisenpartikeln bei der Beurteilung von experimentell induzierten Osteosarkomen der Weichteile

The findings help to advance the understanding of the distribution and kinetics of intravenous-injected small particles of iron oxide in osteosarcoma-like tumors. A first-pass accumulation of iron oxide could be documented by MR imaging in the periphery of osteosarcomas. Due to sieving of iron oxide particles by liver, spleen, and bone marrow, the signal intensity at 45 minutes after the injection of iron oxide returned to 89% (150 mumol iron oxide/kg) and 95% (50 mumol iron oxide/kg) of the preinjection intensity.

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Vergleich zwischen GE- und SE-Sequenzen in der MRT nach i.v. Applikation von superparamagnetischen Eisenpartikeln bei der Beurteilung von experimentell induzierten Osteosarkomen der Weichteile

Abstract: Superparamagnetic iron oxides induce signal alterations in tumours of the peripheral soft tissue. GE sequences proved to be more sensitive than SE sequences.

Cited by 3 publications

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Delivery of contrast agents for magnetic resonance imaging, computed tomography, nuclear medicine and ultrasound

Delivery of contrast agents for magnetic resonance imaging, computed tomography, nuclear medicine and ultrasound

Extra- and intracellular accumulation of ultrasmall superparamagnetic iron oxides (USPIO) in experimentally induced abscesses of the peripheral soft tissues and their effects on magnetic resonance imaging

Mechanisms of Accumulation of Small Particles of Iron Oxide in Experimentally Induced Osteosarcomas of Rats: A Correlation of Magnetic Resonance Imaging and Histology

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