Vergleich des Regenerativen Zytokinprofils von Adipose Derived Stromal Cells (ASCs) Gewonnen Mittels Abdominoplastik, Suction Assisted
                    Liposuction (SAL) und Ultrasound Assisted Liposuction (UAL)

Aitzetmüller, Matthias M.; Machens, Hans‐Günther; Schilling, Arndt F.; Duscher, Dominik

doi:10.1055/s-0043-118596

Cited by 3 publications

(4 citation statements)

References 57 publications

(59 reference statements)

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“… 31 , 32 Furthermore, it has been repeatedly stated that even ultrasound-assisted aspiration liposuction does not compromise the regenerative potential of ASCs. 26 , 27 , 33 , 34 Therefore, it can be assumed that the preparation of a cell therapeutic based on lipoaspirate samples can be effectively performed as a point-of-care procedure.…”

Section: Discussionmentioning

confidence: 99%

Arthroscopy with Lipoaspirate and Plasma Infiltration Using Adipose-Derived Stem Cells Plus Platelet-Rich Plasma: Harvesting and Injection for Arthroscopic Treatment of Cartilage Defects of the Knee

Weninger,

Feichtinger,

Steffel

et al. 2023

Arthroscopy Techniques

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Section: Discussionmentioning

confidence: 99%

Arthroscopy with Lipoaspirate and Plasma Infiltration Using Adipose-Derived Stem Cells Plus Platelet-Rich Plasma: Harvesting and Injection for Arthroscopic Treatment of Cartilage Defects of the Knee

Weninger,

Feichtinger,

Steffel

et al. 2023

Arthroscopy Techniques

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“…Liposuction can be considered rather a domain of plastic surgery. However, it is not only used for aesthetic purpose [ 46 , 47 – 51 ]; it can become part of various disciplines, bariatric operations, in lipedema (and) for reconstruction (e.g., “lipofilling”). …”

Section: Corner Pointsmentioning

confidence: 99%

“…Over the last years, treatment with own fatty tissue has been established, in particular, in plastic surgery [ 51 , 53 – 55 ]. There is an option to use endogeneous “material”.…”

Section: Corner Pointsmentioning

confidence: 99%

Interdisciplinary aspects of abdominal and plastic surgery – what does the (abdominal) surgeon need to know?

Kraus,

Damert,

Meyer

2023

Innovative Surgical Sciences

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Introduction The aim was to reflect the established interdisciplinary aspects of general/abdominal and plastic surgery by means of a narrative review. Methods: (i) With specific references out of the medical literature and (ii) own clinical and perioperative as well as operating technical and tactical management experiences obtained in surgical daily practice, we present a choice of options for interdisciplinary cooperation that could be food of thought for other surgeons. Content – Decubital ulcers require pressure relieve, debridement and plastic surgery coverage, e.g., by a rotation flap plasty, V-Y flap or “tensor-fascia-lata” (TFL) flap depending on localization (sacral/gluteal defects, ischiadic tuber). – Coverage of soft tissue defects, e.g., after lymph node dissection, tumor lesions or disturbance of wound healing can be managed with fasciocutaneous or muscle flaps. – Bariatric surgery: Surgical interventions such as butt lift, tummy tuck should be explained and demonstrated in advance and performed commonly after reduction of the body weight. – Abdominoperineal rectum extirpation (APE): Holm’s procedure with greater circumferential extent of resection at the mesorectum and the insertion site of the levator muscle at the anal sphicter muscle resulting in a substantial defect is covered by myocutaneous flap plasty. – Hernia surgery: Complicated/recurrent hernias or abdominal wall defect can be covered by flap plasty to achieve functional reconstruction, e.g., using innervated muscle. Thus, abdominal wall can respond better onto changes of pressure and tension. – Necrotising fasciitis: Even in case of suspicious fasciitis, an immediate radical debridement must be performed, followed by intensive care with calculated antibiotic treatment; after appropriate stabilization tissue defects can be covered by mesh graft of flap plasty. – Soft tissue tumor lesions cannot be resected with primary closure to achieve appropriate as intended R0 resection status by means of local radical resection all the time – plastic surgery expertise has to be included into interdisciplinary tumor concepts. – Liposuction/-filling: Liposuction can be used with aesthetic intention after bariatric surgery or for lipedema. Lipofilling is possible for reconstruction and for aesthetic purpose. – Reconstruction of lymphatic vessels: Lymphedema after tumor operations interrupting or blocking lymphatic drainage can be treated with microsurgical reconstructions (such as lympho-venous anastomoses, lympho-lymphatic anastomoses or free microvascular lymph node transfer). – Microsurgery: It is substantial part of modern reconstructive plastic surgery, i.e., surgery of peripheral nerves belongs to this field. For visceral surgery, it can become important for reconstruction of the recurrent laryngeal nerve. – Sternum osteomyelitis: Radical debridement (eventually, complete sternal resection) with conditioning of the wound by vacuum-assisted closure followed by plastic surgery coverage can prevent chronification, threatening mediastinitis, persisting infectious risk, long-term suffering or limited quality of life. Summary The presented selection of single topics can only be an excerpt of all the options for surgical cooperation in daily clinical and surgical practice. Outlook An interdisciplinary approach of abdominal and plastic surgery is characterized by a highly developed cooperation in common surgical interventions including various techniques and tactics highlighting the specifics of the two fields.

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“…Die dritte Generation (VASER-assistierte Absaugung) wurde von Duscher et al mit der zweiten Generation verglichen [30]. Die Überlebensfähigkeit und die adipogene Differenzierungskapazität zeigten sich vergleichbar, während die osteogene Differenzierungsfähigkeit bei den ASCs, welche durch VASER gewonnen wurden, erhöht war [37]. Ein In-vivo-murines Wundheilungsmodell zeigte keine signifikanten Unterschiede in der Wundheilung zwischen den ASCs der 2. und 3.…”

Section: Ultraschallassistierte Liposuktion (Ual)unclassified

Der Einfluss von Gewinnung und Verarbeitung auf das Regenerationspotenzial von Fettstammzellen und die Adipozytenvitalität

Klietz

Kückelhaus

Wiebringhaus

et al. 2021

Handchir Mikrochir Plast Chir.

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ZusammenfassungDer autologe Lipotransfer stellt eine etablierte Innovation der Plastischen Chirurgie dar. Als Methode zur Mammarekonstruktion und -augmentation bietet er eine klinisch immer bedeutender werdende Alternative zu den konventionellen Verfahren wie der Lappenchirurgie oder der Verwendung von Silikonimplantaten.Der Erfolg oder Misserfolg des autologen Lipotransfers hängt größtenteils vom Überleben der im Fett befindlichen Fettstammzellen ab.Diese Überlebensrate ist wiederum von einem komplexen Zusammenspiel der Zwischenschritte bei der Fettabsaugung und potenzieller Aufbereitung des Fettgewebes abhängig.Dieses Review beleuchtet die entscheidenden Prinzipien zur Erzielung optimaler Ergebnisse.

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Vergleich des Regenerativen Zytokinprofils von Adipose Derived Stromal Cells (ASCs) Gewonnen Mittels Abdominoplastik, Suction Assisted Liposuction (SAL) und Ultrasound Assisted Liposuction (UAL)

Abstract: UAL and SAL lipoaspirates are suitable for obtaining functional ASCs and are comparable to minimally manipulated cells from abdominoplasty resections.

Cited by 3 publications

References 57 publications

Arthroscopy with Lipoaspirate and Plasma Infiltration Using Adipose-Derived Stem Cells Plus Platelet-Rich Plasma: Harvesting and Injection for Arthroscopic Treatment of Cartilage Defects of the Knee

Arthroscopy with Lipoaspirate and Plasma Infiltration Using Adipose-Derived Stem Cells Plus Platelet-Rich Plasma: Harvesting and Injection for Arthroscopic Treatment of Cartilage Defects of the Knee

Interdisciplinary aspects of abdominal and plastic surgery – what does the (abdominal) surgeon need to know?

Der Einfluss von Gewinnung und Verarbeitung auf das Regenerationspotenzial von Fettstammzellen und die Adipozytenvitalität

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