Ventriculo-Peritoneal Shunt Infections in a Tertiary Center, 3 Years Experience

Dinçer, Emre; Karabulut, Nazan Dalgıç

doi:10.5222/tp.2021.29392

Cited by 3 publications

(2 citation statements)

References 18 publications

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“…Previous studies have stated that the most common bacteria causing meningitis in the use of a VP shunt is Staphylococcus bacteria [16]. Despite advances in surgical techniques and infection control, infections associated with VP shunt placement still range from 5 to 18% and are mostly caused by gram-positive bacteria (59%) [17]. This is in accordance with the results of a study which found that 24% of samples with the use of a VP shunt and the most common cause were gram-positive bacteria, namely Staphylococcus sp.…”

Section: Discussionmentioning

confidence: 99%

Microorganism and Antibiotik Sensitivity Pattern of Children Bacterial Meningitis in Denpasar Tertiary Hospital 2019-2020

Mahalini¹,

Mustika²,

Suwarba³

2022

AJP

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Introduction: Bacterial meningitis is a severe acute infection of the central nervous system that caused by bacteria.The antibiotic should be given immediately. An appropriate antibiotic may reduce the morbidity and mortality caused by bacterial meningitis. This study aims to evaluate the bacterial pattern and antibiotic sensitivity in children bacterial meningitis at tertiary hospital in Denpasar. Material and methods: This retrospective descriptive study was using a cross-sectional design that involved pediatric patients aged 1 month-18 years old with suspected bacterial meningitis who underwent a lumbar puncture at Sanglah Hospital from January 2019 to December 2020. The diagnosis of bacterial meningitis was made based on cerebrospinal fluid culture and antibiotic sensitivity test. Samples were taken by consecutive sampling method and would be excluded if the medical record was incomplete. Results: There were ninety five pediatric patients treated with suspected meningitis. Thirty-three subjects had positive cerebrospinal fluid culture results with eight of them were contaminants. The proportion of bacterial meningitis was 26.3%. Bacterial meningitis was more common in children younger less than two years old (72%) compare with older children. The most gram-positive bacteria were Staphylococcus sp. while for gram-negative was Acinetobacter sp. and Sphingomonas paucimobilis. Vancomycin had a high sensitivity (92.8%) for gram-positive therapy, while for gram-negative it was cephalosporin drug which is ceftriaxone and cefepime (63.6%). Conclusion: Ceftriaxone as the main choice of empiric therapy still has high sensitivity to gram-negative bacteria but low sensitivity to gram-positive bacteria.

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Section: Discussionmentioning

confidence: 99%

Microorganism and Antibiotik Sensitivity Pattern of Children Bacterial Meningitis in Denpasar Tertiary Hospital 2019-2020

Mahalini¹,

Mustika²,

Suwarba³

2022

AJP

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“…∼26,000 TRY [30] Cardiac implantable electronic devices ∼1.2-3.6% [31] Staphylococcus aureus (MSSA and MRSA), Staphylococcus epidermidis (MSSE and MRSE), other CoNS, other Grampositive cocci, GNB, Candida and Aspergillus (fungi) [32] . Intervention [33]: Removal of all CIED hardware and prolonged intravenous antibiotics…”

Section: Introductionmentioning

confidence: 99%

Biomaterial strategies to combat implant infections: new perspectives to old challenges

Braem

Kamarudin

Bhaskar

et al. 2023

International Materials Reviews

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Peri-implant infection is rapidly becoming anif not the mostimportant clinical challenge for indwelling medical devices. To alleviate the global rise in antibiotic use for the treatment of such infections, a plethora of biomaterials/bioengineering-based antimicrobial strategies are emerging to restrict or ideally to eliminate microbial adhesion and biofilm formation on implant surfaces. Yet, the development of such approaches faces specific challenges, like biocompatibility concerns, reduced antimicrobial effectiveness, long-term stability issues and antibiotic resistance development, which limit translation to the clinic. This review provides insights into the antimicrobial activity of current state-of-the-art biomaterial-based approaches to address the aforementioned issues. Translational research strategies and regulatory framework are also emphasised as key elements facilitating clinical implementation of anti-infective biomaterials. This review closes with the vision that the integration of computational tools and experimental databases using artificial intelligence (AI) would provide new insights for the accelerated development of next-generation biomaterial-based antimicrobial strategies.

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Costs of pediatric hydrocephalus treatment for the Brazilian public health system in the Northeast of Brazil

Soriano

Melo

2022

Childs Nerv Syst

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Ventriculo-Peritoneal Shunt Infections in a Tertiary Center, 3 Years Experience

Cited by 3 publications

References 18 publications

Microorganism and Antibiotik Sensitivity Pattern of Children Bacterial Meningitis in Denpasar Tertiary Hospital 2019-2020

Microorganism and Antibiotik Sensitivity Pattern of Children Bacterial Meningitis in Denpasar Tertiary Hospital 2019-2020

Biomaterial strategies to combat implant infections: new perspectives to old challenges

Costs of pediatric hydrocephalus treatment for the Brazilian public health system in the Northeast of Brazil

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