Ventricular Septal Defect in a Houbara Bustard (Chlamydotis undulata macqueenii)

Ta, Bailey; Kinne, Jöerg

doi:10.2307/1593033

Cited by 10 publications

(5 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cardiovascular defects in birds have been investigated far less than in mammals, but have been described for numerous species (see Kubale et al, 2018). Ventricular septal defects have been described in a juvenile houbara bustard (Chlamydotis undulata macqueenii) (Bailey & Kinne, 2001) and for penguins as well as various species of caged birds (Laughlin et al, 2016). Experimental manipulation of the circulation of chicken embryos has been used to investigate causal mechanisms for mammalian cardiac defects (Aranega et al, 1985;Broekhuizen et al, 1999;Ward et al, 2005;Midgett & Rugonyi, 2014), so presumably some, if not all, of the cardiovascular defects that occur in adult mammals also can appear in adult birds.…”

Section: (A) Intracardiac Shuntsmentioning

confidence: 99%

Cardiovascular shunting in vertebrates: a practical integration of competing hypotheses

2019

View full text Add to dashboard Cite

This review explores the long‐standing question: ‘Why do cardiovascular shunts occur?’ An historical perspective is provided on previous research into cardiac shunts in vertebrates that continues to shape current views. Cardiac shunts and when they occur is then described for vertebrates. Nearly 20 different functional reasons have been proposed as specific causes of shunts, ranging from energy conservation to improved gas exchange, and including a plethora of functions related to thermoregulation, digestion and haemodynamics. It has even been suggested that shunts are merely an evolutionary or developmental relic. Having considered the various hypotheses involving cardiovascular shunting in vertebrates, this review then takes a non‐traditional approach. Rather than attempting to identify the single ‘correct’ reason for the occurrence of shunts, we advance a more holistic, integrative approach that embraces multiple, non‐exclusive suites of proposed causes for shunts, and indicates how these varied functions might at least co‐exist, if not actually support each other as shunts serve multiple, concurrent physiological functions. It is argued that deposing the ‘monolithic’ view of shunting leads to a more nuanced view of vertebrate cardiovascular systems. This review concludes by suggesting new paradigms for testing the function(s) of shunts, including experimentally placing organ systems into conflict in terms of their perfusion needs, reducing sources of variation in physiological experiments, measuring possible compensatory responses to shunt ablation, moving experiments from the laboratory to the field, and using cladistics‐related approaches in the choice of experimental animals.

show abstract

Section: (A) Intracardiac Shuntsmentioning

confidence: 99%

Cardiovascular shunting in vertebrates: a practical integration of competing hypotheses

2019

View full text Add to dashboard Cite

show abstract

“…There have been a few notable reported exotic cases, in particular a captive houbara bustard (Chlamydotis undulata) and Humboldt penguin. The bustard in question died at 6 months old, presenting with retarded growth; upon necropsy it was found the heart was twice the anticipated size and a ventricular septal defect was located [43]. In this case it was believed to be a genetically linked defect, supporting the theory that avian species can develop defects both as a result of in ovo factors and also genetic factors [43].…”

Section: Ventricular Septal Defectsmentioning

confidence: 65%

“…A ventricular septal defect occurs when the wall in between the left and right ventricle does not fully develop, resulting in a left to right blood shunt. Often associated with this defect is ventricular hypertrophy which later develops in order to maintain cardiac output [43]. There have been a few notable reported exotic cases, in particular a captive houbara bustard (Chlamydotis undulata) and Humboldt penguin.…”

Section: Ventricular Septal Defectsmentioning

confidence: 99%

“…The bustard in question died at 6 months old, presenting with retarded growth; upon necropsy it was found the heart was twice the anticipated size and a ventricular septal defect was located [43]. In this case it was believed to be a genetically linked defect, supporting the theory that avian species can develop defects both as a result of in ovo factors and also genetic factors [43]. In the incidence of the penguin, a ventricular septal defect was detected after the Humbolt similarly presented with retarded growth.…”

Section: Ventricular Septal Defectsmentioning

confidence: 99%

See 1 more Smart Citation

Avian Cardiovascular Disease Characteristics, Causes and Genomics

Kubale¹,

Merry²,

Miller³

et al. 2018

Application of Genetics and Genomics in Poultry Science

View full text Add to dashboard Cite

Cardiovascular disease is common in avian species and increasing commercial economic losses and demand for healthcare in the household/smallholding veterinary sector has resulted in increased research into these disorders. This in turn has highlighted the importance of breeding, genetic testing and possibilities for future prognostic and diagnostic testing. Research into avian cardiovascular genetics has rapidly accelerated. Previously much work was undertaken in mammals with information extrapolated and transferred to birds. Birds have also been used to model cardiovascular disease and therefore knowledge has become enriched due to this endeavour. Increasingly, the avian genome is being analysed in its own right. This work is assisted by the growing number of avian genomes being published. In 2015, Nature published news on the 'Bird 10K' project, which aims to sequence 10,500 extant bird species. By 2018, the Avian Genomes Consortium had published the sequences of 45 species/34 orders. This review investigates a range of avian cardiovascular disorders in order to highlight their pathologies, epidemiology and genetics in addition to avian models of heart disease. With the availability of more reference genomes, increases in the number and magnitude of avian studies and more advanced technologies, the genetics behind avian cardiovascular disorders is being unravelled.

show abstract

“…The VSD to date has been described in several domesticated (Hamlin and others , Halnan , Knauer and others , Hawe , Donnelly and others , Vörös and others ) and non‐domesticated animals (Cook and others , Shinohara and Nishimura , Swindle and others , Johnson and others , Binhazim and others , Boon and others , Moore and others , Suedmeyer and others , Koie and others , Dennison and others ), including avian (Einzig and others , Harari and Miller , Bailey and Kinne ) and reptile (Brockman and Kennedy, ) species. In dogs, VSD has been found in conjunction with other cardiac defects in almost half of the cases (48%), usually pulmonic stenosis (65%)(Oliveira and others ).…”

Section: Discussionmentioning

confidence: 99%

Ventricular septal defect in a ferret (Mustela putorius furo)

Girolamo¹,

Critelli

Zeyen

et al. 2012

J of Small Animal Practice

View full text Add to dashboard Cite

A four-year-old, castrated male ferret (Mustela putorius furo) was evaluated because of a one-year history of sporadic cough. On physical examination a grade 5 of 6 holosystolic murmur was audible over the right apex of the heart. Radiographic findings included the presence of air bronchograms in apical lobes accompanied by pulmonary venous congestion. Colour Doppler echocardiography revealed a left-to-right shunting compatible with a ventricular septal defect. Medical therapy was initiated at the time of the diagnosis. The ferret was presented again 2 months after the initial examination for coughing and respiratory distress. Echocardiographic findings included tricuspid regurgitation, relative enlargement of left-atrial diameter and decreased systolic function, with presence of pleural effusion. Thoracocentesis was performed and the therapeutic plan was revised. In the following months the symptoms did not recur. In the authors' opinion this is the first report to describe the clinical findings of isolated ventricular septal defect in the ferret. Congenital heart defects are rare in this species, the present ferret being only the second case described.

show abstract

Ventricular Septal Defect in a Houbara Bustard (Chlamydotis undulata macqueenii)

Cited by 10 publications

References 2 publications

Cardiovascular shunting in vertebrates: a practical integration of competing hypotheses

Cardiovascular shunting in vertebrates: a practical integration of competing hypotheses

Avian Cardiovascular Disease Characteristics, Causes and Genomics

Ventricular septal defect in a ferret (Mustela putorius furo)

Contact Info

Product

Resources

About