Ventricular rupture secondary to cardiac metastasis of transitional cell carcinoma of the bladder

Abstract

We report a patient with transitional cell carcinoma of the bladder who had metastatic nodules in the myocardium of the left ventricle and tumour emboli in the left circumflex artery which caused myocardial infarction with ventricular rupture and haemopericardium. Cardiac metastasis of transitional cell carcinoma of the bladder is discussed and the literature reviewed.

Solitary metastasis of urothelial carcinoma of the urinary bladder to the heart: An unusual clinical manifestation

“…Finally, clinical manifestations were present, although cardiac metastases are usually clinically silent and rarely produce symptoms, the most common being pericardial effusion or cardiac tamponade. 3,4 Because of the advanced stage at diagnosis, curative surgery is only possible for a minority of patients with cardiac metastatic tumors, especially when this is the only site of dis-ease and the primary tumor is under control or when metastases result in right ventricular outflow tract obstruction. 4,5 In this setting, surgical debulking may ameliorate symptoms and prolong survival, as may chemotherapy, which our patient elected.…”

A Complex Cardiac Mass Originating from Interatrial Septum in a Patient with History of Kidney Cancer: A Case Report and Literature Review

“…Cardiac metastasis of transitional cell carcinoma has been previously reported in the right ventricle, left atrium, and pericardium. Malde et al reported a case of papillary muscle rupture following myocardial infarct secondary to tumor emboli [ 10 ]. The mechanism of spread is hypothesized to be either hematogenous, with macro- or micro-dissemination through the IVC typically involving the endocardium and cavity, or through the lymphatic system, which involves the myocardium and pericardium.…”

Metastatic urothelial carcinoma to pericardia manifested by dyspnea from cardiac tamponade during systemic chemotherapy: case report and literature review

“…Including the present case, 14 cases of symptomatic cardiac metastases from UC have been reported so far: 7 bladder cancers and 7 renal pelvic cancers. [4][5][6][7][8][9][10][11][12][13][14][15][16] (Table-1). There have been 3 reported cases of cardiac tamponade from urothelial carcinoma.…”