Ventricle-Brain Ratio, Computed Tomographic Density, and Brain Area in 50 Schizophrenics

Pearlson, Godfrey D.

doi:10.1001/archpsyc.1989.01810080020003

Cited by 142 publications

(56 citation statements)

References 55 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Also, the largest previous study using direct head circumference measurements (Weinberger et al 1987) reported mean values very close to those for male subjects and controls in the current study. Even if height was systematically underestimated by 2.5 cm, results for male subjects would continue to be significant; however, methodological differences between this and other studies (Andreasen et al 1986;Grove et al 1991;Ingraham et al 1991;Jones and Lewis 1991;Pearlson et al 1989;Zipursky et al 1991) could account for variable findings, since a range of brain imaging and morphometric assessments were used.…”

Section: Discussionmentioning

confidence: 55%

Increased head circumference in schizophrenia

Bassett

Chow

Bury

et al. 1996

Biological Psychiatry

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 55%

Increased head circumference in schizophrenia

Bassett

Chow

Bury

et al. 1996

Biological Psychiatry

View full text Add to dashboard Cite

“…This may also be due to the subjects selected from our Faculty of Medicine and High-school for Sports. Accordingly, it was reported that higher occupational status subjects had, on average, larger brains than did lower occupational status subjects (Pearlson et al, 1989;Andreasen et al, 1990;Rushton, 1992; see also Rushton, 1997, pp. 118 ±125).…”

Section: Discussionmentioning

confidence: 99%

Magnetic resonance imaging brain size/IQ relations in Turkish University students

Tan

Polat

et al. 1999

Intelligence

View full text Add to dashboard Cite

The relation of IQ (Cattell's Culture Fair Intelligence Test) to brain size was studied in 103 right-and left-handed men and women at Atatu Èrk University in eastern Turkey. Cerebral areas were measured on a midsagittal section of the brain using MRI. An overall correlation of 0.40 was found between MRI-measured total area and IQ thereby further supporting the IQ±brain size hypothesis. Additional analyses suggested that these results may need qualification. In men, only anterior cerebral area correlated with IQ. In women, total and posterior cerebral areas were correlated with IQ. Other results varied by handedness.

show abstract

“…SSCr is the area of the suprasellar cistern divided by the brain area (at the level of frontal horns) (19,27). VBr was obtained by dividing the lateral ventricle area by the brain area (at the same level) (28).…”

Section: Methodsmentioning

confidence: 99%

Diagnosing dementia and normal aging: clinical relevance of brain ratios and cognitive performance in a Brazilian sample

Chaves

Ilha

Maia

et al. 1999

Braz J Med Biol Res

View full text Add to dashboard Cite

The main objective of the present study was to evaluate the diagnostic value (clinical application) of brain measures and cognitive function. Alzheimer and multiinfarct patients (N = 30) and normal subjects over the age of 50 (N = 40) were submitted to a medical, neurological and cognitive investigation. The cognitive tests applied were Mini-Mental, word span, digit span, logical memory, spatial recognition span, Boston naming test, praxis, and calculation tests. The brain ratios calculated were the ventricle-brain, bifrontal, bicaudate, third ventricle, and suprasellar cistern measures. These data were obtained from a brain computer tomography scan, and the cutoff values from receiver operating characteristic curves. We analyzed the diagnostic parameters provided by these ratios and compared them to those obtained by cognitive evaluation. The sensitivity and specificity of cognitive tests were higher than brain measures, although dementia patients presented higher ratios, showing poorer cognitive performances than normal individuals. Normal controls over the age of 70 presented higher measures than younger groups, but similar cognitive performance. We found diffuse losses of tissue from the central nervous system related to distribution of cerebrospinal fluid in dementia patients. The likelihood of case identification by functional impairment was higher than when changes of the structure of the central nervous system were used. Cognitive evaluation still seems to be the best method to screen individuals from the community, especially for developing countries, where the cost of brain imaging precludes its use for screening and initial assessment of dementia.

show abstract

Ventricle-Brain Ratio, Computed Tomographic Density, and Brain Area in 50 Schizophrenics

Cited by 142 publications

References 55 publications

Increased head circumference in schizophrenia

Increased head circumference in schizophrenia

Magnetic resonance imaging brain size/IQ relations in Turkish University students

Diagnosing dementia and normal aging: clinical relevance of brain ratios and cognitive performance in a Brazilian sample

Contact Info

Product

Resources

About