Venous Thromboprophylaxis in Spine Surgery

Alvarado, Anthony M.; Porto, Guilherme; Wessell, Jeffrey; Buchholz, Avery L.; Arnold, Paul M.

doi:10.1177/2192568219858307

Cited by 28 publications

(26 citation statements)

References 23 publications

(54 reference statements)

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“…Although the prevalence and risk factors for developing a VTE after spinal surgery are still debated, hesitation among surgeons to start VTE prophylaxis immediately postoperatively remains prevalent (Alvarado et al 2020, Ploumis et al 2010). Epidural haematoma is a serious complication after spine surgery, which is thought to be aggravated by pharmacologic anticoagulation (Glotzbecker et al 2010).…”

Section: Discussionmentioning

confidence: 99%

The risks and benefits of early venous thromboembolism prophylaxis after elective spinal surgery: A single-centre experience

Kiguchi

Schobel

TenEyck

et al. 2021

Journal of Perioperative Practice

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Background There is a wide ranging incidence of venous thromboembolism after surgery and it continues to be a major cause of morbidity after spinal procedures.This study’s aim was to investigate the relationship between timing and administration of venous thromboembolism (VTE) pharmacologic chemoprophylaxis after spinal surgery and the resulting VTE and bleeding complications by reviewing current practices and outcomes at a high-volume single institution to better define opportunities for perioperative intervention to prevent VTE without increasing bleeding complications. Methods All patients who underwent elective one or two-stage lumbar spinal fusion procedures were identified. A logistic regression was used to evaluate (1) risk of symptomatic VTE within 30 days of surgery and (2) bleeding-related complications. The odds of developing a VTE as well as bleeding-related complications were compared among the three treatment groups: no chemoprophylaxis, chemoprophylaxis < 24h of surgery and chemoprophylaxis given > 24h post-surgery. Results When adjusted for doses administered, the odds of developing a postoperative VTE within 30 days were 0.189 (95% confidence interval (0.044, 0.808)) in patients who received anticoagulation < 24h postoperatively, compared to those who received no anticoagulation (p = 0.025). There was no difference in bleeding rates. Conclusion Patients undergoing elective spinal surgery who received anticoagulation within 24h of the conclusion of their procedure had an 81% reduction in the odds of developing a deep vein thrombosis within 30 days with no significant difference in bleeding complications.

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Section: Discussionmentioning

confidence: 99%

The risks and benefits of early venous thromboembolism prophylaxis after elective spinal surgery: A single-centre experience

Kiguchi

Schobel

TenEyck

et al. 2021

Journal of Perioperative Practice

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“…There is no consensus on a postoperative protocol for venous thrombosis prophylaxis after spinal surgery ( Alvarado et al, 2020 ). Recommendations regarding mechanical versus chemical prophylaxis vary greatly among institutions.…”

Section: Ivcf For Orthopaedic Management Of Vtementioning

confidence: 99%

The application of inferior vena cava filters in orthopaedics and current research advances

Wang

Zhou

et al. 2022

Front. Bioeng. Biotechnol.

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Deep vein thrombosis is a common clinical peripheral vascular disease that occurs frequently in orthopaedic patients and may lead to pulmonary embolism (PE) if the thrombus is dislodged. pulmonary embolism can be prevented by placing an inferior vena cava filter (IVCF) to intercept the dislodged thrombus. Thus, IVCFs play an important role in orthopaedics. However, the occurrence of complications after inferior vena cava filter placement, particularly recurrent thromboembolism, makes it necessary to carefully assess the risk-benefit of filter placement. There is no accepted statement as to whether IVCF should be placed in orthopaedic patients. Based on the problems currently displayed in the use of IVCFs, an ideal IVCF is proposed that does not affect the vessel wall and haemodynamics and intercepts thrombi well. The biodegradable filters that currently exist come close to the description of an ideal filter that can reduce the occurrence of various complications. Currently available biodegradable IVCFs consist of various organic polymeric materials. Biodegradable metals have shown good performance in making biodegradable IVCFs. However, among the available experimental studies on degradable filters, there are no experimental studies on filters made of degradable metals. This article reviews the use of IVCFs in orthopaedics, the current status of filters and the progress of research into biodegradable vena cava filters and suggests possible future developments based on the published literature by an electronic search of PubMed and Medline databases for articles related to IVCFs searchable by October 2022 and a manual search for citations to relevant studies.

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“…Remiantis apžvalginiais straipsniais, galima teigti, kad kompresinės kojinės sumažina giliųjų venų trombozės dažnį [32]. Mechaninės profilaktikos priemonės stuburo chirurgijoje taip pat rekomenduojamos [33].…”

Section: Intraoperacinis Etapasunclassified

Protocol of Spinal Deformity Surgery and Anaesthesia in Children and Adult: Recommended Preoperative and Perioperative Diagnostic and Treatment Algorithm in Spinal Deformity Surgery

Šalaševičius

Savičienė

Alsytė

et al. 2021

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Venous Thromboprophylaxis in Spine Surgery

Cited by 28 publications

References 23 publications

The risks and benefits of early venous thromboembolism prophylaxis after elective spinal surgery: A single-centre experience

The risks and benefits of early venous thromboembolism prophylaxis after elective spinal surgery: A single-centre experience

The application of inferior vena cava filters in orthopaedics and current research advances

Protocol of Spinal Deformity Surgery and Anaesthesia in Children and Adult: Recommended Preoperative and Perioperative Diagnostic and Treatment Algorithm in Spinal Deformity Surgery

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