Venous Thromboembolism and Route of Delivery – Review of the Literature

Abstract

Venous thromboembolism events are important causes of maternal death during pregnancy and the postpartum period worldwide. A review of the literature with the objective of evaluating venous thromboembolism events in the puerperium according to the route of delivery was performed through a bibliographic survey in the Medline, LILACS and Scielo databases. We observed that patients submitted to cesarean sections present a significantly higher risk of developing venous thromboembolism when compared with those who undergo spontaneous vaginal delivery. The pathophysiological bases for this difference were explored and described in this review, as well as the indications of prophylaxis and treatment. Doctors and health professionals must be continuously vigilant regarding this condition, since it is associated with high morbidity and mortality.

Development and validation of a technology for obstetric intraoperative care safety

“…Prophylaxis verification for venous thromboembolism was added to LIVESCO, as pregnancy is a period in which anatomical and hormonal changes occur in women. Thus, venous thromboembolism risk increases five to ten times, increasing (up to 20 times) in the puerperium, when compared to that of non-pregnant women (20) . A fact that constitutes a warning to professionals in terms of prophylaxis and treatment is that women undergoing cesarean section have a higher risk of developing venous thromboembolism than those who perform spontaneous vaginal delivery.…”

Prospective cohort study of the venous system through duplex mapping in the puerperal pregnancy cycle

“…As gestantes foram recrutadas na sala de pré-parto antes do procedimento cirúrgico, sendo Apesar do risco de tromboembolismo venoso (TEV) após parto cesariano ser 3 a 4 vezes maior se comparado ao parto vaginal, não encontramos trombose venosa superficial e profunda em nossa amostra (Evangelista et al, 2018;S. K. Ismail et al, 2012;Sénat et al, 2016).…”

Uso de anticoagulante no ciclo gravídico-puerperal e os efeitos adversos relacionados: revisão de literatura

“…A ativação do fator tecidual e do fator X, podendo ter formação de mínimas quantidades de trombina, resultando na ativação de plaquetas e cofatores ativados (Va e VIIa), que ocasiona uma rápida resposta de coagulação. Todo esse esquema contribui para o desenvolvimento de trombose durante o período de puerpério (Evangelista, Slompo & Timi, 2018).…”