Venous and arterial ammonia in dairy cows with fatty liver and hepatic failure

Mudroň, Pavol; Rehage, J.; Höltershinken, M.; Scholz, H

doi:10.17221/5693-vetmed

Cited by 4 publications

(3 citation statements)

References 12 publications

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“…This is in agreement with previous reports showing that high systemic NH 3 compromise initial embryo growth in the oviduct which could lead to embryo mortality [53]. Elevated ammonia concentration has also been linked to impaired fertility and poor reproductive health [54]. Serum ammonia concentrations were the highest in cows with dystocia and the least in those with retained placenta (Figure 2).…”

Section: Discussionsupporting

confidence: 92%

Minerals and Serum Metabolites Profile in Cows Reared on Natural Pastures in a Semi-Arid Area

Molefe,

Mwanza

2023

World J. Veter. Sci.

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This study aimed to profile minerals and metabolite levels in cows solely reliant on natural pastures. Mineral plays a significant role in cattle production and reproduction. Measures of serum metabolites are good indicators in disease diagnosis and nutritional status of animals. A total of 179 blood samples were collected from cases of cows of different ages and breeds experiencing dystocia (n=50), downer cow syndrome (n=34), vaginal prolapse (n=16), retained placenta (n=13), and abortions (n=69) following reports submitted to the North-West (NWU) Animal Hospital in Mafikeng Campus. Analysis of minerals and serum metabolite were done using ICP-MSand IDEXX Catalyst Chemistry Analyser. The data were coded and analysed using the Statistical Software for Social Scientists (SPSS) version 25. Descriptive statistics were used to show the distribution of the minerals and serum metabolites levels across the reproductive conditions. The results were significantly different at 5% (P <0.05). Low zinc levels were seen in cows with abortions and dystocia. In downer cow syndrome, the levels of iron, magnesium and phosphorus were high. Low Iodine levels were seen in cows with vaginal prolapse, retained placenta, abortion and dystocia. Low phosphorus levels were noted in cows with vaginal prolapse. Significant differences were seen in the concentrations of Urea/BUN, Total bilirubin, Aspartate amino-transferase (AST), ammonia and lipase. The levels of minerals and serum metabolites are significant indicators in cows presenting with different reproductive conditions and could affect production.

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Section: Discussionsupporting

confidence: 92%

Minerals and Serum Metabolites Profile in Cows Reared on Natural Pastures in a Semi-Arid Area

Molefe,

Mwanza

2023

World J. Veter. Sci.

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“…The liver has great powers of regeneration and more overt clinical signs associated with its failure do not appear until some 70-80% of the functional capacity is lost [1].…”

Section: Discussionmentioning

confidence: 99%

“…The liver has great powers of regeneration and more overt clinical signs associated with its failure do not appear until some 70-80% of the functional capacity is lost. Obscure signs of liver disease are therefore much more common than overt signs of liver failure [1,2]. Liver abscesses have capsules that vary in thickness, and range in size from a minute pinpoint to over 15 cm in diameter.…”

Section: Introductionmentioning

confidence: 99%

Liver Abscess in Dromedary Camels (Camelusdromedaries): Oxidative Stress Biomarkers and Proinflammatory Cytokines

El-Deeb¹,

Fouda²

2013

J Veterinar Sci Technol

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Background: The characteristic clinical manifestations, oxidative stress markers and proinflammatory Cytokines in liver abscess in camel are poorly defined.Objective: Our objectives were to investigate liver abscess in camel at the slaughter house and to address its effect on blood cellular and biochemical values particularly oxidative stress markers and proinflammatory cytokines.Methods: Thirty-five camels with liver abscesses and 15 healthy camels were included in this study. Complete blood picture, and selected biochemical parameters were carried out. Bacteriological examination was also carried out.Results: Clinical signs were recorded. The hematological picture of diseased camels revealed reduction in the total erythrocytic count and hemoglobin level associated with elevation in leucocytic count and neutrophils percentage. The biochemical analysis of serum samples revealed increase in the levels of liver enzymes associated with reduction in the levels of total proteins, albumen and glucose levels in diseased camels when compared to their levels in healthy ones. Increased levels of lipid peroxidation and glucose 6-phosphate dehydrogenase with significant reduction in the levels of superoxide dismutase, catalase and glutathione were evident when compared to their levels in healthy camels. There was elevation in the levels of TNF-α, IFN-γ, IL-1α, IL-1β, IL-6 and IL-10 in diseased camels when compared to their levels in normal ones. The isolated bacteria from liver abscess were Fusobacterium necrophorum, Corynebacterium psuedotuberclosis, Escherichia coli, and Staphylococcus spp. Conclusions:Oxidative stress and proinflammatory Cytokines could be used as biomarkers of liver abscess in camel. It is one of the best antioxidant supplied organs. An important function of the liver is the detoxification of drugs, chemicals and toxic materials, with the subsequent release of free radicals [14,15]. To the best of our knowledge little is known about liver abscess as a disease condition in camels, therefore the main objective of this study was to throw the light on liver abscess in camel at the slaughter house and to address the effects on blood cellular and biochemical values particularly oxidative stress markers and proinflammatory cytokines. Liver Abscesses in Dromedary Camels Materials and Methods AnimalsA total of 50 one-humped camels (Camelus dromedarius) were involved in this study. Their age ranged between 3.5 and 7 years old. All camels were examined carefully before slaughtering. The camels divided into two groups. The 1 st was healthy camels (n=15) and the second was camels with liver abscess (n=35). Journal of Veterinary Science & TechnologyCitation: El-Deeb WM, Fouda TA (2013) Liver Abscesses in Dromedary Camels (Camelus dromedaries): Oxidative Stress Biomarkers and Proinflammatory Cytokines.

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Metabolic and Endocrine Diseases

2017

Veterinary Medicine

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Venous and arterial ammonia in dairy cows with fatty liver and hepatic failure

Cited by 4 publications

References 12 publications

Minerals and Serum Metabolites Profile in Cows Reared on Natural Pastures in a Semi-Arid Area

Minerals and Serum Metabolites Profile in Cows Reared on Natural Pastures in a Semi-Arid Area

Liver Abscess in Dromedary Camels (Camelusdromedaries): Oxidative Stress Biomarkers and Proinflammatory Cytokines

Metabolic and Endocrine Diseases

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