Euadenia trifoliolata (Capparaceae) is a tropical forest plant. It is used in the pharmacopoeia for its medicinal properties and for that it is overexploited. Information on propagation techniques of E. trifoliolata domestication and its wild management are still missing. The study conducted on nurseries aimed to obtain some young plants from cutting stems. For this purpose, cuttings harvested in different areas (Adzopé, Banco, Ehotilé Islands and Marahoué) were used and some parameters like viability, time of emission of shoot and the first leaf, number of leaves, length and width of leaves, length of stems and diameter of stems were evaluated according to the origin and treatment of the cuttings and the growing medium (unheated soil, heated soil (45 °C), soil treated with extracts of Ricinus communis (Euphorbiaceae) without heating and heated soil (45 °C) and treated with extracts of R. comminus). Results showed that the viability varied according locations and treatments. Shoot emission time varied from 13.32 ± 1.12 days to 12.94 ± 1.38 days. The emission time of the first leaf ranged from 22.65 ± 3.82 to 24 ± 6.32 days. There was also variation in the number of leaves (from 5.32 ± 0.19 to 5.13 ± 0.27), the leaf length (from 50.74 ± 1.50 to 53.20 ± 2.47 cm) and leaf width (from 25.96 ± 1.37 to 39.14 ± 2.26 cm). The stem length oscillated between 25.68 ± 1.28 and 29.01 ± 1.50 cm and the stem diameter fluctuated from 12.52 ± 0.51 to 12.06 ± 0.57 cm. E. trifoliolata can be regenerated from cuttings and maintained its therapeutic potential. Cuttings treated with newsprint gave the best results whatever the culture medium.