Vegetarian diet and reduced uterine fibroids risk: A case–control study in Nanjing, <scp>China</scp>

Shen, Yang; Wu, Yanting; Lü, Qing; Ren, Mulan

doi:10.1111/jog.12834

Cited by 19 publications

(34 citation statements)

References 32 publications

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“…Several studies support an inverse association between leiomyoma and a great intake of fruits and vegetables, particularly for citrus fruit [46], cruciferous vegetables (broccoli, cabbage, and Chinese cabbage), tomatoes, and apples [46]. Fruit and vegetables contain various nutrients that may decrease fibroid risk through inhibition of proliferation, apoptosis, or hormone-dependent pathways [47].…”

Section: Lifestyle and Dietmentioning

confidence: 99%

Epidemiology and Risk Factors of Uterine Fibroids

Pavone

Clemenza

Sorbi

et al. 2018

Best Practice & Research Clinical Obstetrics & Gynaecol

240

140

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Risk factors, both modifiable and non-modifiable, are associated with the development of fibroids. These include age, race, endogenous and exogenous hormonal factors, obesity, uterine infection, and lifestyle (diet, caffeine and alcohol consumption, physical activity, stress, and smoking). Some of the epidemiological data were conflicting; consequently, further studies are needed to better understand the factors that influence fibroid prevalence.

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Section: Lifestyle and Dietmentioning

confidence: 99%

Epidemiology and Risk Factors of Uterine Fibroids

Pavone

Clemenza

Sorbi

et al. 2018

Best Practice & Research Clinical Obstetrics & Gynaecol

240

140

View full text Add to dashboard Cite

show abstract

“…The positive impact of an active health-promoting lifestyle on the development of UFs is a trendy subject to explore. Exposure to different environmental and nutritional factors, such as plastic products, cosmetics, and other chemicals, as well as the intake of soybean milk, food additives, sweeteners, and preserved foods can increase the risk of UFs [4,30]. Furthermore, the incidence of UFs has been shown to be greater in populations consuming more red meat, for example, beef [31].…”

Section: Diet Healthy Lifestyle and Uterine Fibroids: An Overviewmentioning

confidence: 99%

Vitamins and Uterine Fibroids: Current Data on Pathophysiology and Possible Clinical Relevance

Ciebiera

Ali

Zgliczyńska

et al. 2020

IJMS

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Uterine fibroid (UF) is the most common benign tumor pathology of the female reproductive organs. UFs constitute the main reason for a hysterectomy and hospitalization due to gynecological conditions. UFs consist of uterine smooth muscle immersed in a large amount of extracellular matrix (ECM). Genetic studies have demonstrated that UFs are monoclonal tumors originating from the myometrial stem cells that have underwent specific molecular changes to tumor initiating stem cells which proliferate and differentiate later under the influence of steroid hormones. There is growing interest in the role of micronutrients, for example, vitamins, in UFs. This article is a comprehensive review of publications regarding the available data concerning the role of vitamins in the biology and management of UFs. In summary, the results showed that some vitamins are important in the biology and pathophysiology of UFs. For example, vitamins A and D deserve particular attention following studies of their influence on the treatment of UF tumors. Vitamins B3, C, and E have not been as widely studied as the abovementioned vitamins. However, more research could reveal their potential role in UF biology.

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“…Several studies have shown a protective effect of vegetable and fruit intake against uterine leiomyomas, most notably with citrus fruit, apples, cabbage, broccoli, and tomatoes [ 30 , 31 , 32 ]. In the US Black Women’s Health Cohort Study, the frequency of food items has been determined on the premise of how many servings are consumed per day or month among women before menopause [ 30 ].…”

Section: Diet and Nutrition In Uterine Leiomyomamentioning

confidence: 99%

Diet and Nutrition in Gynecological Disorders: A Focus on Clinical Studies

et al. 2021

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A healthy lifestyle and a balanced diet play a paramount role in promoting and maintaining homeostatic functions and preventing an array of chronic and debilitating diseases. Based upon observational and epidemiological investigations, it is clear that nutritional factors and dietary habits play a significant role in gynecological disease development, including uterine leiomyoma, endometriosis, polycystic ovary syndrome, and gynecological malignancies. Diets rich in fruits and vegetables, Mediterranean diets, green tea, vitamin D, and plant-derived natural compounds may have a long-term positive impact on gynecological diseases, while fats, red meat, alcohol, and coffee may contribute to their development. Data regarding the association between dietary habits and gynecological disorders are, at times, conflicting, with potential confounding factors, including food pollutants, reduced physical activity, ethnic background, and environmental factors limiting overall conclusions. This review provides a synopsis of the current clinical data and biological basis of the association between available dietary and nutritional data, along with their impact on the biology and pathophysiology of different gynecological disorders, as well as an outlook on future directions that will guide further investigational research.

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Vegetarian diet and reduced uterine fibroids risk: A case–control study in Nanjing, China

Cited by 19 publications

References 32 publications

Epidemiology and Risk Factors of Uterine Fibroids

Epidemiology and Risk Factors of Uterine Fibroids

Vitamins and Uterine Fibroids: Current Data on Pathophysiology and Possible Clinical Relevance

Diet and Nutrition in Gynecological Disorders: A Focus on Clinical Studies

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