VBN‐based nomograms provide critical voiding parameters which can be used for invasive or non‐invasive flow interpretation of women at risk of obstruction over time

Abstract

Using a mathematical model of micturition and data extracted from PFs, two nomograms on urethral obstruction and detrusor contractility were designed. This tool offers a rapid and practical method for the clinician to follow women at risk of obstruction over time. Its applications will be the purpose of further studies. Neurourol. Urodynam. 36:37-42, 2017. © 2015 Wiley Periodicals, Inc.

Which parameters, related to the female urethra and pelvic floor, determine therapy selection for recurrent female stress urinary incontinence: ICI‐RS 2023?

“…27,28 Bladder outlet obstruction (BOO) in women can be challenging to measure reproducibly, even using a pressure-flow study. Several nomograms have been proposed, of which none has yet been proven to be preferential, [29][30][31] although the Solomon-Greenwell nomogram has recently gained popularity (Figure 3). 31 After tension-free sling surgery for SUI, BOO may be more common than previously thought.…”

A response to Dr. Petros and a note on models and theories

“…Lastly, if we take IT to be a theory in the sense we described in the opening paragraph, then it is perhaps controversial to claim that IT “is the only universal theory yet published for bladder function,” as Dr. Petros does in his letter. Dr. Valentini (who incidentally also raised questions about the breadth of our review 2 ) introduced the VBN theory containing several mathematical components that can estimate critical voiding parameters during UDS, which can then be used for treatment recommendations 15 . Maciá Pérez et al 9 built a fully mathematical model with a trained artificial neural network used as the neural control scheme and reported being able to accurately identify and simulate “four or less dysfunctions” of the LUT.…”

“…Dr. Valentini (who incidentally also raised questions about the breadth of our review 2 ) introduced the VBN theory containing several mathematical components that can estimate critical voiding parameters during UDS, which can then be used for treatment recommendations. 15 Maciá Pérez et al 9 built a fully mathematical model with a trained artificial neural network used as the neural control scheme and reported being able to accurately identify and simulate "four or less dysfunctions" of the LUT. A main motivating factor for creating our review was to ensure that future modeling efforts like these do not talk past each other, and are constructed in such a way that each can extend on ideas from the other.…”

RE to Jaskowak D, Nunez R, Ramachandran R, Alhajjar E, Yin J, Guidoboni G, Danziger ZC Mathematical modeling of the lower urinary tract: A review. 2022; 41(6): 1305–1315. 10.1002/nau.24995

“…To the Editor, As co-speaker during the ICI-RS meeting 2023, I was very surprised to hear in my session a reference to a review article published in NAU by Jaskovaw et al 1 who, despite a large panel of students that "helped them survey the literature and compile the database on which this review is base" ignored some mathematical models of micturition and of the lower urinary tract as well as their clinical applications (PUMA 2 and VBN [3][4][5][6][7][8] ). Figure 1 gives a description of the main published models and their characteristics.…”