Vascular Quality of Life Questionnaire-6 facilitates health-related quality of life assessment in peripheral arterial disease

Nordanstig, Joakim; Wann-Hansson, Christine; Karlsson, Jan; Lundström, Mats; Pettersson, Magnus; Morgan, M.

doi:10.1016/j.jvs.2013.08.099

Cited by 97 publications

(79 citation statements)

References 19 publications

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“…These results suggest that Vascu-QOL can be a potential quantitative method to suspect the existence of CLI in dialysis PAD patients. One more advantage of VascuQOL over SPP is easy for every health professional to administer, score, and analyze without using any specific measuring machine [26].…”

Section: Discussionmentioning

confidence: 99%

“…Vascu-QOL consists of simple questionnaire, but the number of questions might be large for older patients. Actually, a trial to reduce the number of questions has been already performed [26]. Several domains such as "Pain", "Symptom," and "Emotional" can be selected and assessed in the future studies to achieve better compliance.…”

Section: Discussionmentioning

confidence: 99%

“…Each question has a 7-point response scale. The score ranges from 1 (worst QOL) to 7 (best QOL) [26]. Fourteen patients (82.4 %) in the non-CLI group and 8 patients (53.3 %) in the CLI group could complete all the questions at all of the three evaluation points.…”

Section: Vascuqolmentioning

confidence: 99%

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Evaluation of vascular quality of life questionnaire in dialysis patients with peripheral arterial disease treated by low-density lipoprotein apheresis

Nagai

Harada

Yokota³

et al. 2016

Ren Replace Ther

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Background: Peripheral arterial disease (PAD) is a common complication in dialysis patients. Early diagnosis and treatment are recommended. Low-density lipoprotein apheresis (LDL-A) is a potential therapy to improve PAD. However, the mechanism has yet to be fully clarified due to lack of established quantitative methods to assess the therapeutic effects of LDL-A treatment. Improvement of skin perfusion pressure (SPP) or ankle brachial index (ABI) is a representative therapy goal, but clinical symptoms were not always consistent with the values of SPP/ABI. Vascular quality of life questionnaire (VascuQOL) was proposed as a disease-specific QOL score, getting validated recently. The possibility of VascuQOL to reflect the severity of PAD in dialysis patients and evaluate the therapeutic effects of LDL-A has yet to be elucidated. Methods: This is an observational study. LDL-A treatment was performed in 32 dialysis patients with PAD. They were divided to critical limb ischemia (CLI) group (17 subjects) and non-CLI group (15 subjects) according to their clinical manifestations. We examined the relationship of PAD severity with SPP, ABI, VascuQOL, and lipid profile such as apoB/apoA-I ratio, malondialdehyde-modified LDL, and remnant-like particles cholesterol. Furthermore, we evaluated these parameters successively to find out a suitable therapeutic marker just after the first LDL-A, at tenth LDL-A, and 1 month after completion of LDL-A treatment. Results: All of the lipid markers were higher in CLI patients, but not significantly different from those in the non-CLI group. They decreased significantly just after LDL-A, although no changes were observed 1 month after completion of LDL-A treatment. ABI was significantly different between the CLI and non-CLI groups, but did not improve by LDL-A treatment. By contrast, SPP was ameliorated significantly and the peak was at tenth LDL-A. Among VascuQOL domains, "Symptom" and "Emotional" domains were significantly different between the CLI and non-CLI groups. The average score of VascuQOL increased successively until 1 month after completion of LDL-A treatment. Conclusions: Several domains of VascuQOL can reflect the severity of PAD in dialysis patients. VascuQOL was a useful marker to show the prolonged therapeutic effects of LDL-A treatment in dialysis patients with PAD, independent of SPP.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Evaluation of vascular quality of life questionnaire in dialysis patients with peripheral arterial disease treated by low-density lipoprotein apheresis

Nagai

Harada

Yokota³

et al. 2016

Ren Replace Ther

View full text Add to dashboard Cite

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“…Furthermore, all items in the VascuQol have seven response options, which could very well be too many. Indeed, in a recent study, Nordanstig et al 7 found through cognitive interviews that many patients mentioned the abundance of response options. This may also cause patients to fill items at random, which influences outcome.…”

Section: Discussionmentioning

confidence: 99%

Test–retest Reliability and Measurement Error Are Excellent for the Dutch Version of the VascuQol Questionnaire in Patients with Intermittent Claudication

Conijn

Loukachov

Bipat

et al. 2015

European Journal of Vascular and Endovascular Surgery

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“…As specified in Appendix 2 (Supporting Information Appendix S2), when assessing GPS outdoor walking capacity in PAD patients, some authors have used the total walking distance measured during a 40-min outdoor walk (Nordanstig et al, 2014a(Nordanstig et al, , 2014b, whereas others have used the highest measured distance between two stops (Le Faucheur et al, 2008Faucheur et al, , 2010Tew et al, 2013). The difference in the outcome measures computed seems to be a direct consequence of the GPS analysis methodology used.…”

Section: Clinical Interpretationmentioning

confidence: 99%

Clinical Interest of Ambulatory Assessment of Physical Activity and Walking Capacity in Peripheral Artery Disease

Müllenheim

Chaudru

Prioux

et al. 2015

Scandinavian Med Sci Sports

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The purpose of the present review was to provide, for the first time, a comprehensive analysis and synthesis of the available studies that highlighted the clinical interest of the ambulatory assessment of either physical activity (PA) or walking capacity in patients with lower extremity peripheral artery disease (PAD). We identified 96 related articles published up to March 2015 through a computer-assisted search of the MEDLINE, EMBASE, and Web of Science databases. Ambulatory-measured PA or related energy expenditure (EE) in PAD patients was performed in 87 of the 96 included studies. The main clinical interests of these measurements were (a) the assessment of PA/EE pattern; (b) the characterization of walking pattern; and (c) the control of training load during home-based walking programs. Ambulatory-measured walking capacity was performed in the remaining studies, using either Global Positioning System receivers or the Peripheral Arterial Disease Holter Control device. Highlighted clinical interests were (a) the assessment of community-based walking capacity; (b) the use of new outcomes to characterize walking capacity, besides the conventional absolute claudication distance; and (c) the association with the patient's self-perception of walking capacity. This review also provides for the clinicians step-by-step recommendations to specifically assess PA or walking capacity in PAD patients.

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Vascular Quality of Life Questionnaire-6 facilitates health-related quality of life assessment in peripheral arterial disease

Abstract: VascuQoL-6 is a valid and responsive instrument for the assessment of health-related quality of life in PAD. The main advantage is the compact format that offers a possibility for routine use in busy clinical settings.

Cited by 97 publications

References 19 publications

Evaluation of vascular quality of life questionnaire in dialysis patients with peripheral arterial disease treated by low-density lipoprotein apheresis

Evaluation of vascular quality of life questionnaire in dialysis patients with peripheral arterial disease treated by low-density lipoprotein apheresis

Test–retest Reliability and Measurement Error Are Excellent for the Dutch Version of the VascuQol Questionnaire in Patients with Intermittent Claudication

Clinical Interest of Ambulatory Assessment of Physical Activity and Walking Capacity in Peripheral Artery Disease

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