Vascular Complications in Renal Transplantation: A Single-Center Experience in 1367 Renal Transplantations and Review of the Literature

Dimitroulis, Dimitrios; Bokos, John; Zavos, G.; Nikiteas, Nikolaos; Karidis, Nikolaos P.; Katsaronis, Paraskevas; Kostakis, A.

doi:10.1016/j.transproceed.2009.02.077

Cited by 158 publications

(152 citation statements)

References 27 publications

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“…The most common vascular complications are transplant renal artery stenosis, transplant renal artery/vein thrombosis, biopsyinduced vascular injuries, pseudoaneurysm formation, and hematomas. 12 Transplant renal artery/vein thrombosis generally occurs during the first 2 postoperative weeks and is reported in up to 6% of kidney transplants. 13,14 In pediatric kidney transplant, graft loss due to thrombosis is a major problem.…”

Section: Discussionmentioning

confidence: 99%

Mean Platelet Volume as a Potential Predictor of Renovascular Thrombosis After Renal Transplant

Sakallı

Baskın²,

Bayrakçı³

et al. 2012

Exp Clin Transplant

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artIClE AbstractObjectives: We sought to evaluate the importance of mean platelet volume as a marker to follow-up, the tendency for hemorrhagic diatheses, and/or thrombotic complications in patients before and after renal transplant. Materials and Methods: Thirty-four patients (aged, 5 to 18 y) were included. Demographics of the patients, cause of chronic renal failure, dialysis modality, duration of dialysis, arterio-venous fistula thrombosis, and posttransplant immunosuppressive regimens were recorded and laboratory variables were evaluated. Results: At the end of the first posttransplant month, mean platelet volume level was decreased significantly when compared with pretransplant levels (8.3 ± 1.5 vs 7.7 ± 0.9; P = .04). A significant increase was observed in platelet levels during posttransplant measures (273.750 ± 97.700 vs 318.740 ± 84.586; P = .02). Prothrombin time and partial thromboplastin time levels did not differ before and after transplant. None of the patients had any thrombotic events and/or renal allograft loss. A negative correlation was observed between mean platelet volume and C-reactive protein (r=-0.53). Mean platelet volume level was not found to be related to the cause of renal failure, pretransplant dialysis modality, or posttransplant immunosuppressive regimens. Conclusions:Platelet numbers increased and mean platelet volume decreased after pediatric renal transplant, but the potential for increased thrombosis was not observed.

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Section: Discussionmentioning

confidence: 99%

Mean Platelet Volume as a Potential Predictor of Renovascular Thrombosis After Renal Transplant

Sakallı

Baskın²,

Bayrakçı³

et al. 2012

Exp Clin Transplant

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“…[5][6][7] Transplant renal vein thrombosis (TRVT) of an allograft has a dramatic clinical presentation and is one of the main causes of early graft dysfunction after renal transplant, with a reported prevalence of 0.1% to 4.2 % of all transplants. 2,[8][9][10][11] Transplant renal vein thrombosis events lead to graft loss and nephrectomy in almost all cases. 5,[12][13][14] The prevalence of TRVT is higher in deceased-donor than in livingdonor transplant.…”

Section: Introductionmentioning

confidence: 99%

“…Other recipient-related risk factors include pretransplant dialysis modality, 22,23 in which peritoneal dialysis is associated with more graft thrombosis than hemodialysis, due to elevated plasma procoagulant factors, hypercoagulable states, including antiphospholipid antibody syndrome, antithrombin deficiency, mutation of factor V Leiden, and the prothrombin gene. 8,12,22,24,25 Perioperative hemodynamic status, 11,26 in which hypotension and dehydration could predispose to acute kidney injury, hypoperfusion, and thrombosis, and primary renal disease such as membranous nephropathy 11,22,[26][27][28] have also been identified as risk factors for venous graft thrombosis.…”

Section: Introductionmentioning

confidence: 99%

“…8,11,12,23,24,26 The following mechanical causes are considered the most common causes of TRVT: a kink in the renal vein, compression by hematomas or lymphoceles, anastomotic stenosis, and extension of an underlying deep venous thrombosis. 10,23,[28][29][30][31] In our experience, compression of the renal vein by the renal artery is another risk factor, especially in contralateral transplant procedures (right kidney into the left iliac fossa and left kidney into the right iliac fossa).…”

Section: Introductionmentioning

confidence: 99%

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Zorkany

Bridson²,

Sharma³

et al. 2017

Exp Clin Transplant

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Transplant renal vein thrombosis usually occurs early after surgery with a reported prevalence of 0.1% to 4.2%. It is a devastating event that ultimately leads to graft loss in almost all cases. There are many predisposing factors related to donor, recipient, surgery, and immunosuppression, with mechanical factors being considered the most common causes of transplant renal vein thrombosis. The clinical manifestations of acute renal vein thrombosis are nonspecific and are not dissimilar to the features of urine leak, urinary obstruction, or severe acute rejection. The diagnosis of transplant renal vein thrombosis depends on a high index of clinical suspicion and duplex ultrasonographic scans. Although venography remains the criterion standard, this procedure is invasive and nephrotoxic, due to use of ionizing contrast agents and also due to exposure to ionizing radiation. There are 2 therapies that have been described in the literature for salvaging a renal allograft with transplant renal vein thrombosis: thrombolytic therapy and surgical thrombectomy. The usual end result is renal allograft nephrectomy because the diagnosis is almost always too late.

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“…External iliac arterial obstruction is relatively rare, which may cause surgical failure and ipsilateral leg ischaemia. Prompt diagnosis and management of this kind of complication is essential to rescue the patient and allograft (4,5). Among the 1217 patients, only four cases were confirmed with external iliac arterial obstruction caused by Satinsky atrauma forceps.…”

Section: Introductionmentioning

confidence: 99%

External Iliac Arterial Obstruction Caused by Satinsky Atrauma Forceps in Renal Transplantation (with Four Case Report)

et al. 2015

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Vascular Complications in Renal Transplantation: A Single-Center Experience in 1367 Renal Transplantations and Review of the Literature

Cited by 158 publications

References 27 publications

Mean Platelet Volume as a Potential Predictor of Renovascular Thrombosis After Renal Transplant

Mean Platelet Volume as a Potential Predictor of Renovascular Thrombosis After Renal Transplant

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External Iliac Arterial Obstruction Caused by Satinsky Atrauma Forceps in Renal Transplantation (with Four Case Report)

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