Vascular Anomalies of the Maxillofacial Region: Diagnosis and Management

Fočo, Faris; Brkić, Amila

doi:10.5772/53853

Cited by 3 publications

(4 citation statements)

References 70 publications

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“…The marker was not expressed by congenital non-progressive hemangiomas, vascular and lymphatic malformations, reactive granulation tissue, oral varix, pyogenic granulomas, epithelioid hemangiomas, or hemangioendotheliomas. 3 , 16 , 17 , 20 , 21 , 23 Our case is in agreement with a study done by Johann et al, 20 which concluded that GLUT1 could be used an auxiliary marker for oral benign vascular lesions.…”

Section: Discussionsupporting

confidence: 90%

“…In the oral cavity, bleeding, ulceration, and infection are the complications that may develop after masticatory minor trauma. 3 Thomas et al 15 reported that infants may experience failure to thrive due to increased metabolic demand from the proliferating tissue, dysphagia from oral or airway obstruction, and feeding problems caused by oral aversion and sensory problems. It is for this reason that authors suggest surgical intervention should be preferred over non-treatment for hemangiomas of the oral cavity unlike active non-intervention for infantile hemangiomas for the skin.…”

Section: Discussionmentioning

confidence: 99%

“… 5 They present more frequently in premature infants with <1,000 g birthweight, firstlings, whites, paternal age <35 years, and infant born to mothers of higher maternal age complicated by hyperemesis, multiple gestations, placenta previa, preeclampsia, and chorionic-villus sampling. 3 , 6 , 7 …”

Section: B Ackgroundmentioning

confidence: 99%

“…Histopathological assessment is subjective and cannot render a correct diagnosis of hemangiomas. 3 Hence, a formulated workup using this immunohistochemical marker and diagnosis using standard terminology is a must for the management of hemangiomas to avoid misinterpretation and reclassification of vascular lesions. This immunohistochemical biomarker GLUT1 has been proven to be a sensitive and specific marker for hemangiomas of the skin, not the mucosa.…”

Section: B Ackgroundmentioning

confidence: 99%

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Isolated Focal Infantile Hemangioma of the Alveolar Ridge with Glucose Transporter-1 Reactivity: An Aberrant Presentation

Natarajan

Shanmugam

Nachiappan

et al. 2021

International Journal of Clinical Pediatric Dentistry

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A bstract Aim and objective To give dental practitioners an insight into the unusual presentation of focal infantile hemangioma on the alveolar ridge showing immunoreactivity to glucose transporter-1 (GLT1). We also recommend the importance of using standardized terminologies to describe the type of hemangioma. Background One of the most commonly seen and misdiagnosed vascular tumors of the skin and soft tissues of the head and neck region in children are infantile hemangiomas. Infantile hemangiomas developing at extracutaneous locations such as the oral cavity are rare, especially without cutaneous involvement. Case description A 9-month-old infant girl presented to the Pediatric Dental Department with a swelling over the maxillary alveolar ridge. The solitary exophytic mass appeared after birth and gradually enlarged in size with episodes of bleeding during feeding. Clinical examination revealed a reddish-pink pedunculated mass that bled profusely on palpation. The lesion was excised by electrocautery and was found to be express glucose transporter-1 confirming the diagnosis of infantile hemangioma. The patient was followed up for 1 year and showed no recurrence. Conclusion Hemangiomas are usually misinterpreted to be pyogenic granulomas, vascular malformation, reactive granulation tissue, or congenital granular cell tumor. This report highlights the use of glucose transporter-1 when there is suspicion of hemangioma for immunohistochemical distinction from other histologically similar vascular lesions of the oral cavity. Clinical significance Dental surgeons treating vascular lesions of the oral cavity should advocate for surgical management techniques that also produce hemostasis due to the risk of intraoperative bleeding. How to cite this article Natarajan D, Muthukali S, Nachiappan N, et al. Isolated Focal Infantile Hemangioma of the Alveolar Ridge with Glucose Transporter-1 Reactivity: An Aberrant Presentation. Int J Clin Pediatr Dent 2021;14(2):319–322.

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