Varicocele in Subfertility: Results of Treatment

Tulloch, W. Selby

doi:10.1016/s0022-5347(05)65499-7

Cited by 27 publications

(21 citation statements)

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“…WHO (1992) found a non-significant difference in the occurrence of azoospermia among infertile males with or without varicocele. Tulloch (1995) considered varicocele as the most common identifiable cause of male subfertility. However, Pasqualotto et al, (2003) observed a common association between azoospermia and varicocele as a result of generalized impairment in sperm production.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Seminal Fluid Parameters, Reproductive Hormones and Testicular Biopsy for non-obstructive Azoospermic Patients with Sertoli cell only Syndrome

Qhraman¹,

Fakhrildin

Bra

2006

SQU Journal for Science

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The aims of this study were (i) to determine the seminal fluid parameters, levels of serum reproductive hormones, testicular size and diameter of seminiferous tubules depending on multiple testicular biopsies from non-obstructive azoospermic (NOA) patients, and (ii) to assess the effect of smoking on concentrations of serum reproductive hormones. Thirty four NOA patients were involved in the present study. The selection of patients was based on an average of 2 pelleting seminal analysis, reproductive hormones profile and diagnostic testicular biopsy. A detailed questionnaire was used to obtain a thorough history from the patients. The results of this study showed that the mean age of NOA patients with Sertoli cell only syndrome (SCOS) was 33.875 years, and 47.05 % of NOA patients have had 2-4 years duration of infertility. Macroscopic examination of seminal fluid appeared to have normal values as reported by WHO. Non-significant (P>0.05) difference was observed for testicular size and diameter of seminiferous tubules between right and left testis. High and abnormal concentrations of serum FSH were registered for NOA patients with SCOS. However, non-significant (P>0.05) differences were reported for concentrations of serum reproductive hormones between smokers and non smokers. In conclusion, testicular biopsy is the useful and predictable diagnostic tool for NOA patients with SCOS. Further studies are needed to explain the etiology, management and prognosis of NOA patients with SCOS.

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Section: Discussionmentioning

confidence: 99%

Evaluation of Seminal Fluid Parameters, Reproductive Hormones and Testicular Biopsy for non-obstructive Azoospermic Patients with Sertoli cell only Syndrome

Qhraman¹,

Fakhrildin

Bra

2006

SQU Journal for Science

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“…Varicoceles are the most commonly seen and correctable cause of male-factor infertility [ 3 ] . Tulloch's report in 1955 [ 4 ] brought to the forefront the proactive treatment and study of varicoceles in the subfertile male.…”

Section: Introduction/backgroundmentioning

confidence: 99%

Microsurgical Subinguinal Varix Ligation: Techniques and Technical Pearls

Bodie

Sandlow

2012

Microsurgery for Fertility Specialists

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Varicocele can be de fi ned as dilatation or tortuosity (varicosity) of the veins of the pampiniform plexus. Varicoceles are present in approximately 15% of unselected men, in 40% of men presenting with primary infertility, and a much higher percentage of couples with secondary infertility [ 1, 2 ] . Varicoceles are the most commonly seen and correctable cause of male-factor infertility [ 3 ] . Tulloch's report in 1955 [ 4 ] brought to the forefront the proactive treatment and study of varicoceles in the subfertile male. Previously, many investigators felt that varicocele repair was cosmetic or only halted testicular injury at best. Since this time, many studies have demonstrated that improvement in semen parameters and chance of pregnancy are very possible with surgical repair of varicoceles.

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“…A theory of insufficient valves or lack of these in the testicular veins seems most convincing. Varicocele has been regarded a curable cause of infertility for dozens of years [3]. Nevertheless, it remains a question as to how much the varicocele causes damage to the reproductive system and the mechanisms through which this occurs.…”

Section: Introductionmentioning

confidence: 99%

Distant 10 years results of laparoscopic operative treatment in patients with varicocele

et al. 2009

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AbstractVaricocele has been regarded a curable cause of infertility for dozens of years. The impact of varicocele treatment in terms of increase in pregnancy rates is a debated issue. We evaluate data from a 10-year cohort of results from laparoscopic operative treatment of varicocele patients according to pregnancy rate, complication rate, and satisfaction with varicocele repair. Ninety seven patients were treated by means of laparoscopy between 1993 and 1996. Ten years after operation questionnaires were sent to all patients. Answers were obtained from 49/97 pts. (50,5%). Details connected with marital status, pregnancy rate, addictions and scrotal pain discomfort were collected. Statistical analysis was performed using chi-square independence test and Spearman’s rank correlation coefficient. After 10 years, 75.5% who answered the questionnaire were fully satisfied with the results of treatment, 12.3% pts of patients were partially satisfied; 63.3% of patients fathered 1 to 3 children. Married patients and those who fathered children were found to be the most satisfied with the operation. We also found the statistically significant negative dependency between smoking addiction and number of children. There were no major complications intra- or postoperatively. No harmful consequences of testicular artery ligation were found. In conclusion, long-time 10 years follow-up enables better estimation of the results of laparoscopic treatment in patients with varicocele. Pregnancy rate may depend not only on varicocele repair but on smoking addiction as well. There is still no evidence of harmful consequences due to testicular artery ligation after varicocele repair

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Varicocele in Subfertility: Results of Treatment

Cited by 27 publications

References 1 publication

Evaluation of Seminal Fluid Parameters, Reproductive Hormones and Testicular Biopsy for non-obstructive Azoospermic Patients with Sertoli cell only Syndrome

Evaluation of Seminal Fluid Parameters, Reproductive Hormones and Testicular Biopsy for non-obstructive Azoospermic Patients with Sertoli cell only Syndrome

Microsurgical Subinguinal Varix Ligation: Techniques and Technical Pearls

Distant 10 years results of laparoscopic operative treatment in patients with varicocele

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