Varicella zoster virus: review of its management

Abstract

Varicella zoster virus (VZV) is one of eight herpes viruses known to infect humans. Primary infection causes varicella (chickenpox), after which virus becomes latent. Years later, VZV reactivates and causes a wide range of neurological diseases. The aim of the present report was to critically examine the published literature to evaluate advantages and limitations of therapy of VZV infection in both immunocompetent and immunocompromised patients. Aciclovir (ACV) has been the drug of choice for many years for the treatment of VZV infections. Recently, other antiviral agents have been developed to overcome the low oral bioavailability of ACV, as well as to provide a more flattering dosage regime. Chickenpox is a benign self-limiting disease in the majority of cases and usually no specific treatment is required. Treatment of shingles is indicated to reduce the acute symptoms of pain and malaise, to limit the spread and duration of the skin lesions and to prevent the development of post-herpetic neuralgia. Different classes of drugs have been used for the treatment of post-herpetic neuralgia. The first choice of any of these medications should be guided by the patient's medical health, the likely adverse effects of the drug and the patient's preference.

Cutaneous Infections Caused by Herpesviridae: A Review

“…However, these methods are more expensive and availability may be limited. 8,20,23,25,26 Serology is sensitive, but not specific with immunoglobulin (Ig) G antibodies to a virus, only indicating a history of infection. Detection of IgM antibodies is mandatory to determine if the infection was recent.…”

Comparison of the Distributions of Seborrheic Dermatitis, Herpes Zoster and Pityriasis Rosea According to Seasons

“…güney Avustralya'da varisella infeksiyonlar› ile mevsimler aras›nda anlaml› iliflki tespit etmifller ve yaz aylar›nda infeksiyonlar›n pik yapt›¤›n› belirtmiflledir 24 . Herpes zosterin mevsimlerle iliflkili olmay›p sporadik olarak y›l›n herhangi bir zaman›nda görüldü¤ünden bahseden araflt›rmalar da mevcuttur [25][26][27] . Glynn ve ark.…”

Oral complications of cancer and cancer therapy

“…Valacyclovir, which has better absorption than acyclovir, may be used for prophylaxis. 136,150 For resistant infection, ganciclovir or foscarnet may be provided. Cytomegalovirus can be managed with valganciclovir, ganciclovir, foscarnet, and cidofovir.…”