Varicella pneumonitis in an immunocompetent patient

Masih, I; Boyle, R; Donnelly, AE; Soye, A; Kidney, Joseph C.

doi:10.1136/bcr.08.2010.3259

Cited by 2 publications

(3 citation statements)

References 14 publications

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“…Varicella pneumonia can be a fatal complication of VZV. Generally, patients present with respiratory distress within one to six days of the onset of a rash [ 5 ]. Although radiographic images cannot be used to definitively diagnose Varicella pneumonia, imaging is useful in narrowing the differential diagnosis.…”

Section: Discussionmentioning

confidence: 99%

“…It was also shown that patients with previous contact with Varicella have an increased risk of morbidity and mortality, and the overall mortality rate from Varicella pneumonia in recent years has been reported to be around 6%, which is significantly decreased from 19% in the late 1960s [ 4 ]. The introduction of the Varicella vaccine has subsequently led to more decline in Varicella incidence and mortality [ 5 ]. By the early 2000s, data show that Varicella associated deaths, including deaths from Varicella pneumonia of adults older than 50 years, dropped by 16% [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

“…In some cases, symptoms of chest discomfort can begin before the onset of the rash. Primary Varicella infection spreads via droplet transfer and the rate of infectivity increases drastically in areas of close proximity [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Healed Varicella Pneumonia: A Case of Diffuse Pulmonary Microcalcifications

Mylarapu¹,

Yarabarla²,

Padilla³

et al. 2021

Cureus

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Varicella pneumonia is a potentially fatal complication of the Varicella-zoster virus (VZV), which causes the well-known chickenpox disease of childhood. Identifying this type of pneumonia by characteristic features is important for radiologists and radiology residents. Typical manifestations of active Varicella pneumonia include diffuse pulmonary nodules, which may mimic other diseases. Healed Varicella pneumonia can present as diffuse, calcified pulmonary micronodules. We describe a case of healed Varicella pneumonia in a patient with a history of remote VZV infection.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Healed Varicella Pneumonia: A Case of Diffuse Pulmonary Microcalcifications

Mylarapu¹,

Yarabarla²,

Padilla³

et al. 2021

Cureus

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Pulmonary Alveolar Microlithiasis

Shaw

McCormack

2020

Semin Respir Crit Care Med

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Pulmonary alveolar microlithiasis (PAM) is a rare, autosomal recessive disorder that is caused by mutations in SCL34A2 that encodes for the type IIb sodium-dependent phosphate cotransporter (Npt2b). The loss of Npt2b transporter function from alveolar epithelial cells results in failure to export inorganic phosphate from the alveolar lining fluid, which then accumulates, binds to calcium, and forms hydroxyapatite microliths. Radiographs and computed tomography of the chest demonstrate hyperdense infiltrates that are often quite dramatic and distinctive, and in many cases, the diagnosis can be made without invasive measures. The most common presenting symptom of PAM is dyspnea on exertion, but the disease is frequently first noted as an incidental finding in asymptomatic patients who have chest films performed for unrelated reasons. Pulmonary fibrosis, pulmonary hypertension, and respiratory failure can develop as the disease progresses, and treatment remains supportive. Lung transplantation is an option for those with end stage disease.

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Varicella pneumonitis in an immunocompetent patient

Cited by 2 publications

References 14 publications

Healed Varicella Pneumonia: A Case of Diffuse Pulmonary Microcalcifications

Healed Varicella Pneumonia: A Case of Diffuse Pulmonary Microcalcifications

Pulmonary Alveolar Microlithiasis

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