Variation of Tpeak‐end, corrected Tpeak‐end, QT, and corrected QT intervals, Tpeak‐end/QT, Tpeak‐end/corrected QT ratios and heart rate variability according to decades in the healthy male subjects aged between 30 and 79 years

Abstract

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. AbstractBackground: Heart rate variability (HRV) is a predictor of cardiac autonomic functions. Ventricular repolarization markers can indicate ventricular arrhythmias. We aimed to evaluate variations of HRV and these repolarization markers in five healthy male groups between age 30 and 79 years according to decades. Materials and Methods:The study group consisted of 500 healthy male subjects between October 2018 and May 2019. The male subjects were divided into five categories according to their ages. Then, electrocardiograms (ECG), transthoracic echocardiograms (TTE), and treadmill exercise test (TET) were performed. T-wave peak-end (Tp-e) interval was defined as the time between the peak point and end of T-wave. Tp-e, corrected Tp-e (cTp-e), QT, and corrected QT (QTc) were measured from the resting ECGs and HRV temporal parameters (SDNN, SDNN Index, SDANN Index, RMSSD, sNN50, and pNN50), and HRV frequency parameters (VLF, LF, HF, and LF/HF) were obtained from 24-hour Holter monitorization recordings. One-way ANOVA test was used for the differences between the groups. Pearson correlation test was used to determine the correlations between the values of all groups. Results:Considering the repolarization parameters, there are significant differences in five groups in terms of Tp-e interval, but not Tp-e/QT and Tp-e/QTc ratios.Considering the HRV parameters, there were statistically significant differences between the five male healthy groups in terms of HRV temporal parameters and there are no significant differences in terms of HRV frequency parameters. Conclusion:As the age increases, basal Tp-e interval increases and HRV temporal parameters decrease significantly in the male subjects aged between 30 and 79 years, but HRV frequency parameters do not change. K E Y W O R D Shealthy male subjects, heart rate variability, Tp-e interval, Tp-e/QT ratio, Tp-e/QTc ratio, variation according to decades | 509 COSGUN aNd OREN

Tpeak‐Tend ECG Marker in Obesity and Cardiovascular Diseases: A Comprehensive Review

“…The authors concluded that as the age increases, basal Tp-e interval increases and HRV temporal parameters decrease significantly in the male subjects aged between 30 and 79 years, but HRV frequency parameters do not change. The relations between the markers from the repolarization group and heart rate variability seem complex and need further evaluation [ 16 ].…”

The relationship between myocardial bridge and frontal QRS‐T angle

“…Cardiac repolarization can traditionally be measured with QT interval, QT dispersion and corrected QT interval (QTc) from 12‐lead surface ECG. 3 , 4 , 5 On the other hands, frontal QRS‐T angle (fQRSTa) is a novel indicator of repolarization and depolarization heterogeneity. The relationship of the fQRSTa in many cardiovascular diseases has been investigated, and its importance in predicting cardiovascular arrhythmias has been demonstrated.…”

“…Cardiac repolarization abnormalities are one of them. Cardiac repolarization can traditionally be measured with QT interval, QT dispersion and corrected QT interval (QTc) from 12‐lead surface ECG 3–5 . On the other hands, frontal QRS‐T angle (fQRSTa) is a novel indicator of repolarization and depolarization heterogeneity.…”