Variation in essential oil components among Iranian Ferula assa-foetida L. accessions

Hassanabadi, Mitra; Ebrahimi, Mohsen; Farajpour, Mostafa; Dejahang, Ata

doi:10.1016/j.indcrop.2019.111598

Cited by 41 publications

(29 citation statements)

References 20 publications

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“…PCA, another unsupervised pattern recognition method, was used to better understand the chemometric characteristics of different pericarps ( Figure 4 b). PCA reflects the importance of each variable in relation to the total variation on each axis; furthermore, it reveals the distribution states of different samples [ 29 , 30 ]. The sample distribution characteristics of prickly ash pericarps from 72 plantations are shown in Figure 4 a.…”

Section: Resultsmentioning

confidence: 99%

“…A total of nine alkylamides were detected in the prickly ash pericarp samples, and alkylamide compositions in the prickly ash pericarps from different plantations were diverse. Genotype and environmental variation affected substance synthesis in the plants, and these substances often increased under external stresses [ 30 ]. Moreover, the differences among the components in Zanthoxylum plants were caused by the sample harvest time and extraction method [ 31 , 32 ].…”

Section: Discussionmentioning

confidence: 99%

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Alkylamide Profiling of Pericarps Coupled with Chemometric Analysis to Distinguish Prickly Ash Pericarps

Tian

Wang

et al. 2021

Foods

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Because of extensive cultivation areas, various cultivars, nonstandard naming notations, and morphology similarity among relative cultivars, adulteration and associated business fraud may happen in the marketplaces of prickly ash pericarps due to higher financial gain and high-frequency trading. This study presents variations in the chemical components and contents of different prickly ash species from different plantations. Alkylamide profiling of pericarps derived from Zanthoxylum armatum, Z. bungeanum, and some relative Zanthoxylum species from 72 plantations across China were tested using ultra-performance liquid chromatography. Then, several chemometrics were applied to classify the prickly ash pericarps to reveal potential indicators that distinguish prickly ash pericarps and to identify the key factors that affect pericarp alkylamide profiling. The dominating alkylamides in the prickly ash pericarps were Z. piperitum (ZP)-amide C (0–20.64 mg/g) and ZP-amide D (0–30.43 mg/g). Alkylamide profiling of prickly ash pericarps varied significantly across species and geographical variations. ZP-amide D in prickly ash pericarps was identified as a potential indicator to distinguish prickly ash species. Longitude and aluminum content in soils were identified as key factors that affected alkylamide profiling of prickly ash pericarps. This study provides a useful tool to classify prickly ash species based on pericarp alkylamide profiling and to determine the key influence factors on pericarp alkylamide variations.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Alkylamide Profiling of Pericarps Coupled with Chemometric Analysis to Distinguish Prickly Ash Pericarps

Tian

Wang

et al. 2021

Foods

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“…The results of the analysis showed that the increase in altitude caused an increase in β-pinene and (Z)-1-propenyl sec-butyl disulfide content, but a reduction in the thiourea content in essential oils. This study showed that altitude was the environmental factor exerting the greatest effect and which caused a great number of variations in the essential oils' chemical components and yield (Hassanabadi et al, 2019). Ferula has many uses in ethnobotany due to its vast phytochemistry but the use of its essential oil has not been seen so much in folk and traditional medicine.…”

Section: Introductionmentioning

confidence: 95%

“…Moghaddam and Farhadi (2015) revealed the correlation between mean annual temperatures and altitude; moreover, the effect of altitude on the yield and composition of essential oil was also studied. The maximum accumulations of essential oil and the presence of a higher number of sulfur compounds in essential oil were found in Ferula assa-foetida L. The study of chemical profiles of nine samples revealed that (E)-propenyl sec-butyl disulfide (37-54%) was the abundant compound with (Z)-propenyl secbutyl disulfide (12-23%) in the essential oils (Hassanabadi et al, 2019). A study showed that decreasing temperature and increasing altitude had a negative correlation with the content of essential oils.…”

Section: Introductionmentioning

confidence: 97%

“…Approximately 160 chemical compounds have been identified in the essential oils of the Ferula species; these chemical compounds are responsible for all biological activities represented by the essential oils and make them a better choice for industrial purposes (Figure 1). These chemical groups are monoterpene hydrocarbons: limonene, myrcene, c-terpinene, p-cymene, δ-3-carene, α-pinene, and β-pinene (Znati et al, 2012;Ben et al, 2016;Khalifaev et al, 2018;Malekzadeh et al, 2018;Asilbekova et al, 2019;Karakaya et al, 2019b;Meena and Swapnil, 2019;Tabari et al, 2019, Topdas et al, 2020; oxygenated monoterpenoids: α-terpinyl acetate, linalool, sabinene, α-terpineol, verbenone, neryl acetate and arcurcumene (Znati et al, 2012;Radulović et al, 2013;Essid et al, 2015;Khoury et al, 2018), sesquiterpene hydrocarbons: germacrene B and D, β-caryophyllene (E)-caryophyllene, bicyclogermacrene,αgurjunene,c-elemene, c-cadinene and δ-cadinene (Zellagui et al, 2012;Essid et al, 2015;Meena et al, 2017b;Topdas et al, 2020;Ahmadi et al, 2020); oxygenated sesquiterpenoids: α-cadinol, caryophyllene oxide, guaiol, α-eudesmol (Z)-ocimenone (E)nerolidol (E)-ocimenone, viridiflorol, carotol, epi-α-muurolol, hinesol, valerianol and spathulenol (Benchabane et al, 2012;Kasaian et al, 2016;Deveci et al, 2018;Akhzari and Saadatfar, 2019;Baccari et al, 2020;Meena et al, 2020a and sulfur-containing metabolites: dimethyl-trisulphide (E)-1propenylsec-butyl disulfide, sec-butyl-(Z)-propenyl-disulphide, disec-butyl-disulphide,phenol 2-methyl-5-(1-methylethyl), sec-butyl-(E)-propenyl-disulphide, 2,5-diethylthiophene, trimethylthiophene and 1-methylpropyl-(1E)-prop-1-en-1-yl-disulfide,bis-[(1methylthio) propyl]-disulfide and 1-methylpropyl-(Z)-prop-1-en-1-yl-disulfide Kasaian et al, 2016;Oüzek et al, 2017;Hassanabadi et al, 2019)…”

Section: Introductionmentioning

confidence: 99%

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Metabolic Profile, Bioactivities, and Variations in the Chemical Constituents of Essential Oils of the Ferula Genus (Apiaceae)

Sonigra

Meena

2021

Front. Pharmacol.

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The genus Ferula is the third largest and a well-known genus of the Apiaceae family. It is categorized in the Peucedaneae tribe and Ferulinae subtribe of the Apiaceae family. At present, about 180 Ferula species have been reported. The genus is mainly distributed throughout central and South-West Asia (especially Iran and Afghanistan), the far-East, North India, and the Mediterranean. The genus Ferula is characterized by the presence of oleo-gum-resins (asafoetida, sagapenum, galbanum, and ammoniacum) and their use in natural and conventional pharmaceuticals. The main phytochemicals present in the genus Ferula are as follows: coumarin, coumarin esters, sesquiterpenes, sesquiterpene lactones, monoterpene, monoterpene coumarins, prenylated coumarins, sulfur-containing compounds, phytoestrogen, flavonoids and carbohydrates. This genus is considered to be a valuable group of medicinal plants due to its many different biological and pharmacological uses as volatile oils (essential oils). Numerous biological activities are shown by the chemical components of the essential oils obtained from different Ferula species. Because this genus includes many bioactivities such as antimicrobial, insecticidal, antioxidant, cytotoxic, etc., researchers are now focusing on this genus. Several reviews are already available on this particular genus, including information about the importance and the uses of all the phytochemicals found in the species of Ferula. Despite this, no review that specifically provides information about the biological activities of Ferula-derived essential oils, has been published yet. Therefore, the present review has been conducted to provide important information about the chemical profile, factors affecting the chemical composition, and biological activities of essential oils of the Ferula species.

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Phytochemical Variation within Aerial Parts of Ferula cupularis Populations, an Endangered Medicinal Plant from Iran

Narimani

Tarakemeh

Moghaddam

et al. 2021

Chemistry & Biodiversity

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Ferula cupularis (Boiss.) Spalik et S. R. Downie is an endangered endemic Iranian medicinal plant with occurrence restricted to Fars and Kohkilooyeh Boyerahmad provinces, Iran. F. cupularis is cited for strong antibacterial activity, usages in foodstuffs preservation, and has long been used by local peoples for ulcer treatment. In this research, the aerial parts of F. cupularis wild populations were collected from three natural habitats: Eqlid-Kaftar (FC1), Kakan (FC2), and Sepidan-Komohr (FC3), to assess phytochemical diversity and antioxidant activity. The quantity of essential oil (EO) ranged remarkably from 0.42 to 0.72 % v/w among the populations. Results obtained from the EO analysis by GC-FID and GC/MS detected up to 56 compounds. α-Pinene (21.65 -31.53 %), sabinene (4.74 -11.39 %), phellandrene (1.78 -5.1 %), δ-3-carene (1.85-7.18 %), limonene (4.12 -7.45 %), (Z)-β-ocimene (9.08-17.64 %), and elemicin (0.23 -5.74 %) were the major compounds of EOs varied significantly among the populations. Moreover, total phenol content (250.54 to 387.45 mg gallic acid/ 100 g dry weight (DW)) and flavonoids (34.38 to 41.12 mg quercetin/100 g DW) of methanolic extracts varied substantially among the populations. Antioxidant activities of F. cupularis EOs and extracts were assessed by DPPH (2,2,1-diphenyl-1-picrylhydrazyl) radical scavenging method. EOs exhibited EC 50 values ranging from 8.88 to 9.67 μg mL À 1 and the EC 50 values for the extract ranged from 941.36 to 1335.96 μg mL À 1 within the populations. Results demonstrated significantly different levels of antioxidant capacities among the studied populations. Monitoring the data, the population collected from Eqlid-Kaftar (FC1) was selected as the most potent population concerning the highest EO content and antioxidant activity level. The obtained data provided new insights for an initial source of breeding plans and ultimately massive production for food and pharmaceutical industries.

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Variation in essential oil components among Iranian Ferula assa-foetida L. accessions

Cited by 41 publications

References 20 publications

Alkylamide Profiling of Pericarps Coupled with Chemometric Analysis to Distinguish Prickly Ash Pericarps

Alkylamide Profiling of Pericarps Coupled with Chemometric Analysis to Distinguish Prickly Ash Pericarps

Metabolic Profile, Bioactivities, and Variations in the Chemical Constituents of Essential Oils of the Ferula Genus (Apiaceae)

Phytochemical Variation within Aerial Parts of Ferula cupularis Populations, an Endangered Medicinal Plant from Iran

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