Metabolic Profile, Bioactivities, and Variations in the Chemical Constituents of Essential Oils of the Ferula Genus (Apiaceae)

Sonigra, Priyankaraj; Meena, Mukesh

doi:10.3389/fphar.2020.608649

Cited by 40 publications

(11 citation statements)

References 160 publications

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“…Some anecdotal observations on livestock report warming effects and an increase in fertility [9]. Like other plant species that are exploited for their therapeutic potential [10][11][12][13][14], FG is among the main plants exploited for its resin [6,15].…”

Section: Introductionmentioning

confidence: 99%

Anthropic Effects on the Biodiversity of the Habitats of Ferula gummosa

et al. 2021

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The uncontrolled exploitation of soil and plants by people has generated important ecological imbalances all over the world. This manuscript focuses its attention on the ecosystem of Ferula gummosa (FG). FG belongs to the Apiaceae family and has a vast distribution from central Asia to South Africa, as well as northwest Iran, including the Zanjan Province. This plant has diverse applications across industrial, forage and medicinal fields. To investigate the effective factors on the FG distribution, four main natural habitats were selected based on field visits and a literature review. Then, environmental factors, such as climate features, topography conditions, and soil characteristics, were collected and analysed. According to the results, the slope is mainly north-northeast with a slope of 55 to 70 degrees, and an elevation range above 2200 m is suitable for the growth of FG in the Zanjan Province. The main companion plants were Silene bupleuroides L. and Thymus kotschyanus. The results show that in the habitats where FG grew, the soil was mostly shallow, sometimes semi-deep and consisting mainly of loam, loamy sand, loamy clay and mostly clay loam with very low salinity (less than 0.7 dS/m), and was in the neutral range of soil acidity (6.9 to 7.33). Soil organic carbon was relatively high, but the amount of nutrients, such as phosphorus and potassium, was less than optimal in these soils. Next, using a Geographic Information System (GIS), maps of homogeneous areas for possible FG establishment across the province were created. In conclusion, the main factors affecting the FG distribution in the Zanjan Province were land use conversion, harvesting fodder and grazing livestock, improper exploitation of rangelands, pests and diseases of Ferula gummosa in the region. The ecological data collected on FG may be useful to understand how human action can affect the existence and extinction of many plant species.

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Section: Introductionmentioning

confidence: 99%

Anthropic Effects on the Biodiversity of the Habitats of Ferula gummosa

et al. 2021

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“…Fiori, and Tephrosia purpurea (L.) Pers. can generally be observed on the rocks and sandy ridges [ 13 , 14 ].…”

Section: Ecology and Vegetation Of Thar Desertmentioning

confidence: 99%

Bioprospecting of endophytes in medicinal plants of Thar Desert: An attractive resource for biopharmaceuticals

Yadav

Meena

2021

Biotechnology Reports

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Highlights Endophytes act as chemical synthesizers of the secondary metabolites of the host plant. Endophytic microflora has been isolated from a wide array of plants. It can serve as a good alternative source for pharmaceutically important compounds. The arid ecosystem of Thar Desert is a rich repository of ethnomedicinal plants. Role of endophytes in the synthesis of bioactive molecules used to enhance production.

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“…This double effect is caused by the permeability of the biological membranes to cationic species, which, in a dose-dependent way, undergo modifications on a part of the sesquiterpenes [ 15 , 16 ]. Among the plants richest in sesquiterpenes, the genus Ferula L. is one of the best known [ 17 , 18 , 19 ]. The genus Ferula L. consists of about 170 species that mainly grow in Northern Africa, Mediterranean areas, and Central Asia [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

The Effect of Ferula communis Extract in Escherichia coli Lipopolysaccharide-Induced Neuroinflammation in Cultured Neurons and Oligodendrocytes

Maiuolo

Bava

Carresi

et al. 2021

IJMS

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In recent decades, interest in natural compounds has increased exponentially due to their numerous beneficial properties in the treatment of various acute and chronic diseases. A group of plant derivatives with great scientific interest is terpenic compounds. Among the plants richest in terpenes, the genus Ferula L. is one of the most representative, and ferutinin, the most common sesquiterpene, is extracted from the leaves, rhizome, and roots of this plant. As reported in the scientific literature, ferutinin possesses antioxidant and anti-inflammatory properties, as well as valuable estrogenic properties. Neurodegenerative and demyelinating diseases are devastating conditions for which a definite cure has not yet been established. The mechanisms involved in these diseases are still poorly understood, and oxidative stress is considered to be both a key modulator and a common denominator. In the proposed experimental system, co-cultured human neurons (SH-SY5Y) and human oligodendrocytes (MO3.13) were treated with the pro-inflammatory agent lipopolysaccharide at a concentration of 1 μg/mL for 24 h or pretreated with ferutinin (33 nM) for 24 h and subsequently exposed to lipopolysaccharide 1 μg/mL for 24 h. Further studies would, however, be needed to establish whether this natural compound can be used as a support strategy in pathologies characterized by progressive inflammation and oxidative stress phenomena.

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Metabolic Profile, Bioactivities, and Variations in the Chemical Constituents of Essential Oils of the Ferula Genus (Apiaceae)

Cited by 40 publications

References 160 publications

Anthropic Effects on the Biodiversity of the Habitats of Ferula gummosa

Anthropic Effects on the Biodiversity of the Habitats of Ferula gummosa

Bioprospecting of endophytes in medicinal plants of Thar Desert: An attractive resource for biopharmaceuticals

The Effect of Ferula communis Extract in Escherichia coli Lipopolysaccharide-Induced Neuroinflammation in Cultured Neurons and Oligodendrocytes

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