Variants of κ-Casein Revealed by Improved Starch Gel Electrophoresis

Neelin, J. M.

doi:10.3168/jds.s0022-0302(64)88699-9

Cited by 90 publications

(18 citation statements)

References 11 publications

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“…Their characteristic nucleotide and aminoacid substitutions are shown on Table 4. The A and the B alleles are the most frequent among all the species of the genus Bos (Neelin, 1964;Woychik, 1964).…”

Section: Csn3 Genementioning

confidence: 99%

Application of Milk Proteins Genetic Polymorphism for Selection and Breeding of Dairy Cows in Bulgaria

Hristov¹,

Teofanova²,

Mehandzhiyski³

et al. 2012

Milk Production - Advanced Genetic Traits, Cellular Mechanism, Animal Management and Health

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Section: Csn3 Genementioning

confidence: 99%

Application of Milk Proteins Genetic Polymorphism for Selection and Breeding of Dairy Cows in Bulgaria

Hristov¹,

Teofanova²,

Mehandzhiyski³

et al. 2012

Milk Production - Advanced Genetic Traits, Cellular Mechanism, Animal Management and Health

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“…The kappa-casein gene (CSN3) is situated on bovine chromosome 6, and its polymorphism has been known since 1964 (Neelin, 1964). Eleven alleles have been identified (Farrell et al, 2004) with A, B and E as the most common (Neubauerová, 2001).…”

mentioning

confidence: 99%

Joint effects of CSN3 and LGB genes on milk quality and coagulation properties in Czech Fleckvieh

Matéjicek¹,

Matějíčková²,

Štípková³

et al. 2008

CZECH J ANIM SCI

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ABSTRACT:The aim of this study was to determine the joint effects of CSN3 and LGB genotypes on parameters of production, quality and coagulation of milk in Czech Fleckvieh cows. Three hundred and twenty-eight Czech Fleckvieh cows were determined for CSN3 (kappa-casein) and LGB (beta-lactoglobulin) genotypes using the PCR-RFLP method, milk quality parameters and coagulation properties. Milk production parameters were obtained from the Official Database of Progeny Testing. Fifteen genotype combinations were detected, with ABAB (21.0%) and AAAB (18.3%) occurring as the most frequent. The observed genes significantly affected the contents of milk protein (crude protein, true protein, casein and whey protein) as well as solid non-fat in milk, casein number and curd quality. BBAA was found to be the genotype with the highest positive impact on most of the milk characteristics evaluated. Whereas ABBB, BBBB, BBAB and ABAB had a positive influence on milk quality and milk coagulation properties, genotypes containing CSN3 allele E had a negative effect. Results presented in this study are applicable in the selection of Czech Fleckvieh cattle.

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“…The C variant of the α s1 -casein locus is found in some European breeds but not in Holsteins (Aschaffenburg and Drewry, 1955;Li and Gaunt, 1972). The κ-casein locus has only two alleles, A and B, with κ-casein A being more frequent than κ-casein B in almost all breeds (Neelin, 1964;Li and Gaunt, 1972). Alleles A and B of the β-lactoglobulin locus are universally present, with a predominance of B in most breeds.…”

Section: Introductionmentioning

confidence: 98%

Genetic polymorphism of milk protein loci in Argentinian Holstein cattle

2000

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Some alleles of milk protein loci are associated with superior cheese production characteristics. The genetic polymorphism of the milk protein loci alphas1-casein, beta-casein, k-casein and beta-lactoglobulin was examined in Argentinian Holstein cattle. Samples from 12 herds of four regions of Córdoba were analyzed by starch gel electrophoresis. The chi² test was used to assess whether the populations were in Hardy-Weinberg equilibrium. Genotypic diversity was analyzed by the Shannon-Weaver index. The observed genotypic frequencies were analyzed by Hedrick's genetic identity and the genetic distance of Balakrishnan and Sanghvi. The allelic and genotypic frequencies were similar to those of other Holstein populations. The genotypic frequencies of the alphas1-casein and beta-casein loci were in equilibrium, whereas in some populations the k-casein and beta-lactoglobulin loci were not. According to the Shannon-Weaver index the total genetic diversity within each herd was greater than 96%. The high values of identity agreed with the low genetic distances among populations. We conclude that there is extensive genetic homogeneity in Holstein cattle in Córdoba Province and that it would be feasible to select for B alleles at the k-casein and b-lactoglobulin loci in order to improve the quality of milk available for cheese manufacturing.

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Variants of κ-Casein Revealed by Improved Starch Gel Electrophoresis

Cited by 90 publications

References 11 publications

Application of Milk Proteins Genetic Polymorphism for Selection and Breeding of Dairy Cows in Bulgaria

Application of Milk Proteins Genetic Polymorphism for Selection and Breeding of Dairy Cows in Bulgaria

Joint effects of CSN3 and LGB genes on milk quality and coagulation properties in Czech Fleckvieh

Genetic polymorphism of milk protein loci in Argentinian Holstein cattle

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