Variability in Survival of Very Low Birth Weight Neonates in Hospitals of India

Murki, Srinivas; Kumar, Neeraj; Chawla, Deepak; Bansal, Anuradha; Mehta, Ashish; Shah, Manish N.; Bhat, Somashekara; Rao, Suman; Bajaj, Naveen; Chowdhary, Gurdev; Singal, Ashwani K.; Jain, Naveen; Baswaraj, T.; Thakre, Rhishikesh

doi:10.1007/s12098-015-1714-6

Cited by 11 publications

(3 citation statements)

References 6 publications

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“…From various previous studies we know that PDA treatment rates depend on the individual centres, treating neonatologist and many other factors [26] The proportion of mothers who received at least one complete course of antenatal steroids was 73.4% in the U.K cohort as compared to only 37.4% in Indian cohort. According to NNAP U.K 2016 data around 86% of eligible mothers received antenatal steroids [27] and in India there is wide variation in steroid uptake rate ranging from 48% to 74% [24,28] from previous studies . The low rate in Indian cohort perhaps presumed to be due to more high risk mother where there was not enough time to give antenatal steroid.…”

Section: Discussionmentioning

confidence: 99%

Comparitive Study Of Short-Term Outcomes Of Preterm Babies ≤30 Weeks In A Tertiary Care Hospital Between India And The U.K

Diggikar¹,

Nagesh²,

Kumar³

et al. 2020

Preprint

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Large numbers of preterm babies are born in middle income countries and neonatal care is improving in these countries. However, comparative clinical outcomes of preterm babies between a tertiary neonatal unit from middle income country and higher income country is limited. Objective: To compare the clinical profile and short-term outcomes of preterm babies ≤ 30 weeks gestation admitted to a tertiary care hospital in India and the U.K. Design: Retrospective cohort observational study using anonymised data from Electronic Patient Records. Setting: Regional tertiary neonatal intensive care unit (NICU) of Manipal Hospitals, Bangalore, India and Homerton University Hospital, London, UK. Participants: Preterm babies born at ≤ 30 weeks gestation admitted to NICUs over five year period (January 2011 to December 2015). Infants with major congenital abnormalities were excluded. Intervention: This is an observational study and routine care was provided as per departmental standard protocols. Main outcome measures: Comparison of neonatal unit mortality between two centres, infant morbidities till discharge from neonatal unit. Results: A total of 740 babies from the U.K centre and 294 babies from Indian centre were enrolled into the study. The mean gestational age in the U.K cohort was 26.6 ± 2.16 weeks, whereas in Indian cohort was 28.4 ± 1.66 weeks (p,<0.001). A significantly lower number of mothers received antenatal steroid (37% v 73%), and higher number of babies were inborn (78.6%) in Indian centre compared to the UK centre (67.3%; p < 0.001). Incidence of BPD and IVH ≥ grade 2 was significantly lower, and ROP needing treatment was significantly higher in Indian centre. Higher number of babies were treated for ductus arteriosus and incidence of culture positive sepsis was significantly high in Indian cohort babies. Survival of babies born at gestational age > 28 weeks was comparable between the U.K and Indian centres. Survival of babies born at ≤ 28 weeks gestation was lower in Indian centre. Conclusions and relevance: The survival of babies above 28 weeks prematurity was comparable between a tertiary care centre in India and the U.K. However, survival of babies ≤ 28 weeks gestation was lower in Indian centre. Incidence of ROP and sepsis was higher in Indian centre.

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Section: Discussionmentioning

confidence: 99%

Comparitive Study Of Short-Term Outcomes Of Preterm Babies ≤30 Weeks In A Tertiary Care Hospital Between India And The U.K

Diggikar¹,

Nagesh²,

Kumar³

et al. 2020

Preprint

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“…Survival rates of VLBW infants in developed countries are reported to be around 85-90% 28, 29 . However, studies from developing countries have shown lower survival rate around 66-74% [30][31][32] . In a recent national study from Turkey of VLBW infants, total survival and survival without major morbidity (de ned as severe IVH, NEC, BPD, and severe ROP) were reported to be 78% and 48%, respectively 23 .…”

Section: Perinatal Featuresmentioning

confidence: 99%

Evaluation of Short-Term Outcomes of Preterm Infants in Two Periods: Vermont Oxford Network Results of a Developing Country Single-Centre Level IIIC Neonatal Intensive Care Unit Experience

Yılmaz

Çebi

Yılmaz

et al. 2022

Preprint

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Purpose: We aimed to compare the short-term outcomes of infants from our level IIIC neonatal intensive care unit (NICU) in two different periods. Method: In this cohort study, data from preterm infants (≤29 weeks and birth weight <1500 g) registered in the Vermont Oxford Network (VON) system were divided into two periods, the first period between January 1, 2005, and December 31, 2009, and the second between January 1, 2010, and December 31,2019.Results: There was no difference in the distribution of preterm infants according to their gestational age subgroups (p=0.169). Although the survival rate increased significantly in the second period (48.1% vs. 64.3%, (p<0.001), there was no difference in terms of survival without morbidity (p=0.480). Conclusion: Analysis of NICU data, through rigorous methods may provide opportunities for the development of quality improvement projects to improve the quality of health care in developing countries.

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“…Among birth cohorts reported from India, VLBW mortality varies from 14.8% to 40.9% (Table 1) [2][3][4][5]. Higher mortality rates have been reported in NICUadmitted cohorts of preterm VLBW neonates [6].…”

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confidence: 99%