Thrombi within the carotid artery usually occur in vessels with severe atherosclerotic lesions and may embolize to cause TIAs and ischemic brain infarctions. The risk factors and potential causes for carotid artery thrombus formation in the absence of atherosclerosis are currently only speculative (e.g., embolic occlusion from a cardiac source). 1 Furthermore, a focal adherent thrombus involving the CCA is even more exceptional because of the rarity of severe atherosclerotic disease in this large and nonturbulent vessel. 1,2 A thrombus lodged in the CCA has been reported in only a very few cases in the literature. 2 We present two patients with a focal adherent thrombus in the CCA diagnosed by ultrasonography and confirmed by neuroimaging. The aim of this work is to investigate the ultrasonographic features of this very uncommon finding in young stroke patients.
CASE 1A 44 year old woman was admitted to our center in October 1998 for an acute brain infarction in the left MCA territory. The brain MR imaging showed multiple vascular ischemic lesions, these being recent in the left ACA and left MCA territories and old in the right ACA territory. The MR angiography revealed an adherent process (0.5 × 4.2 cm) in the left CCA that was confirmed by CT angiography (Fig. 1). Neither MR angiography nor CT angiography showed any typical signs of a dissection of the left CCA but did show a focal adherent thrombus, resulting in a CCA stenosis of 70 to 80% in lumen diameter reduction. Color duplex flow imaging using a transmission frequency of 4.0 MHz (Acuson 128 XP/10, Mountain View, CA) revealed (1) a slightly decreased flow in the left ICA (PSV = 66 cm/s; EDV = 31 cm/s) as compared with the right ICA (PSV = 76 cm/s; EDV = 37 cm/s) and (2) turbulences manifested by an aliasing phenomenon without significant increase of the blood flow velocities in the left CCA (PSV = 75 cm/s; EDV = 20 cm/s) versus those in the right CCA (PSV = 67 cm/s; EDV = 15 cm/s). Color duplex flow imaging also showed a regular adherent isoechoic lesion on the posterior wall in the left CCA (Fig. 2), with dimensions of 0.4 × 3.8