Value of pulmonary rehabilitation in patients with idiopathic pulmonary fibrosis

Rifaat, Nizar; Anwar, Esam; Ali, Yosra Mohamed; Ellabban, Abdou; Hasan, Ali A.

doi:10.1016/j.ejcdt.2014.06.004

Cited by 15 publications

(18 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The age group was matched with the results of Abou Youssuf H. et al; however, the official ATS/ERS/JRS/ALAT guidelines 2011 stated that IPF occurs in the sixth and seventh decades [13,14]. The higher incidence of DPLD in the female population in the studied group was consistent with Abou Youssuf et al and Rifaat et al who found out that the majority of the studied population were females [13,15]. Additionally, it was in agreement with Hassan who studied the comparison of FVC, FVC/DLCO, and TLC/DLCO as an indicator for interstitial lung disease in patients with scleroderma [16].…”

Section: Discussionsupporting

confidence: 80%

Diffusion lung capacity for carbon monoxide correlates with HRCT findings in patients with diffuse parenchymal lung disease

Hieba¹,

Shaimaa²,

Dina³

et al. 2020

Egypt J Bronchol

View full text Add to dashboard Cite

Diffusion lung capacity for carbon monoxide correlates with HRCT findings in patients with diffuse parenchymal lung disease. Background Diffuse parenchymal lung diseases (DPLDs) affect the alveolar epithelium, pulmonary capillary endothelium, basement membrane, and perivascular and perilymphatic tissues. High-resolution computed tomography (HRCT) of the chest is the gold standard modality for diagnosing DPLD. Pulmonary function tests usually show a restrictive defect in spirometry. Single breath diffusion lung capacity for carbon monoxide (DLCO-SB) technique is used to assess the diffuse parenchymal lung diseases, as there is thickening of the alveolar membrane and diminished total lung capacity due to interstitial processes with severe decline in the transfer factor. The aim of this work was to correlate between Warrick’s HRCT fibrosis score and DLCO-SB in DPLD and to assess the possibility of using DLCO as an only tool to follow up DPLD to avoid repeated radiation exposure of the patients in HRCT chest (decrease need for radiological follow-up) or vice versa. Results This work recruited 89 patients over a period of 10 months duration, 74.2% of them were females. The Warrick’s score, ground-glass opacity, irregular pleural margin, subpleural cyst, honeycombing, and septal and subpleural lines were represented as 96.6%, 70.8%, 55.1%, 49.4%, and 48.3% respectively in HRCT of DPLD. Warrick’s score and its subscores (severity score, extent score, alveolitis score, and fibrosis score) were associated with a highly significant decrease in different pulmonary function indices (FVC, FEV1, TLC, and DLCO) with P value 0.001. A highly significant correlation between DLCO grades and total score grades was found with P value 0.001, and 86.8% of the patients with severe DLCO affection showed severe degree of total fibrosis score. Conclusions Both DLCO-SB and HRCT fibrosis scores were significantly correlated. Lifelong follow-up of function and structure of the lung in DPLD is needed by HRCT and DLCO. In an attempt to minimize repeated radiation exposure and reduce cost, we suggest DLCO to be used alone for longer follow-up periods rather than HRCT chest.

show abstract

Section: Discussionsupporting

confidence: 80%

Diffusion lung capacity for carbon monoxide correlates with HRCT findings in patients with diffuse parenchymal lung disease

Hieba¹,

Shaimaa²,

Dina³

et al. 2020

Egypt J Bronchol

View full text Add to dashboard Cite

show abstract

“…The full-text versions of the remaining articles were reviewed for eligibility resulting in the exclusion of 224 for the reasons noted. Ultimately, 62 studies were included from the search, reporting on 60 unique patient samples 23 25–86…”

Section: Resultsmentioning

confidence: 99%

Exercise-based rehabilitation for major non-communicable diseases in low-resource settings: a scoping review

et al. 2019

View full text Add to dashboard Cite

IntroductionWhile there is substantial evidence for the benefits of exercise-based rehabilitation in the prevention and management of non-communicable disease (NCD) in high-resource settings, it is not evident that these programmes can be effectively implemented in a low-resource setting (LRS). Correspondingly, it is unclear if similar benefits can be obtained. The objective of this scoping review was to summarise existing studies evaluating exercise-based rehabilitation, rehabilitation intervention characteristics and outcomes conducted in an LRS for patients with one (or more) of the major NCDs.MethodsThe following databases were searched from inception until October 2018: PubMed/Medline, Embase, CINAHL, Cochrane Library, PsycINFO and trial registries. Studies on exercise-based rehabilitation for patients with cardiovascular disease, diabetes, cancer or chronic respiratory disease conducted in an LRS were included. Data were extracted with respect to study design (eg, type, patient sample, context), rehabilitation characteristics (eg, delivery model, programme adaptations) and included outcome measures.ResultsThe search yielded 5930 unique citations of which 60 unique studies were included. Study populations included patients with cardiovascular disease (48.3%), diabetes (28.3%), respiratory disease (21.7%) and cancer (1.7%). Adaptations included transition to predominant patient-driven home-based rehabilitation, training of non-conventional health workers, integration of rehabilitation in community health centres, or triage based on contextual or patient factors. Uptake of adapted rehabilitation models was 54%, retention 78% and adherence 89%. The majority of the outcome measures included were related to body function (65.7%).ConclusionsThe scope of evidence suggests that adapted exercise-based rehabilitation programmes can be implemented in LRS. However, this scope of evidence originated largely from lower middle-income, urban settings and has mostly been conducted in an academic context which may hamper extrapolation of evidence to other LRS. Cost-benefits, impact on activity limitations and participation restrictions, and subsequent mortality and morbidity are grossly understudied.

show abstract

“…Wilches et al [ 9 ] indicated that in chronic pulmonary patients like TB patients, although receiving all the pharmacological efforts available, they generally continue having physical limitations as the great inflammatory component causes serious injuries that trigger fibroblastic reaction, fibrosis and chest wall retraction, affecting mobility, which compromises pulmonary expansion. PR programs have been reported to result in improved long term outcomes in patients with chronic lung diseases [ 9 , 24 , 25 ]. Since there is a high prevalence of the chronic respiratory symptoms and pulmonary dysfunctions in PLWHA, this indicates the need for further intervention to reduce the long term impact of these symptoms in patients who would have been successfully treated so as to prevent lung damage caused by the disease.…”

Section: Main Textmentioning

confidence: 99%

Human immunodeficiency virus associated pulmonary conditions leading to hospital admission and the pulmonary rehabilitation services received by patients at two central hospitals in Harare

et al. 2018

View full text Add to dashboard Cite

ObjectiveUse of highly active antiretroviral therapy has led to marked reductions in the incidence of HIV-associated opportunistic infections but has had comparatively less impact on the incidence of some pulmonary diseases. This study was done to determine the pulmonary conditions leading to hospital admissions in people living with HIV/AIDS at two central hospitals in Zimbabwe and the pulmonary rehabilitation intervention received.ResultsA total of 92 participants were recruited of which 60 (65.2%) were females. The mean age of the participants was 41.3 years (SD = 9.1). The most common pulmonary condition leading to hospital admission was tuberculosis in 53 (57.6%). About 52 (56.6%) of the participants suffered from pulmonary complications in the last 6 months, 48 (92.3%) were admitted and 26 (50.0%) of the participants received physiotherapy treatment during their admission. None of the participants indicated that they once attended an outpatient pulmonary rehabilitation clinic. Respiratory complication is one of the leading causes of morbidity associated with HIV but no pulmonary rehabilitation services are being offered to these patients. There is need for introduction of pulmonary rehabilitation programs for people living with HIV/AIDS in the current setting.

show abstract

Value of pulmonary rehabilitation in patients with idiopathic pulmonary fibrosis

Cited by 15 publications

References 20 publications

Diffusion lung capacity for carbon monoxide correlates with HRCT findings in patients with diffuse parenchymal lung disease

Diffusion lung capacity for carbon monoxide correlates with HRCT findings in patients with diffuse parenchymal lung disease

Exercise-based rehabilitation for major non-communicable diseases in low-resource settings: a scoping review

Human immunodeficiency virus associated pulmonary conditions leading to hospital admission and the pulmonary rehabilitation services received by patients at two central hospitals in Harare

Contact Info

Product

Resources

About