Value of enhanced transrectal ultrasound targeted biopsy for prostate cancer diagnosis: a retrospective data analysis

Abstract

The combined use of CE-TRUS and RTE is feasible and allows for targeted biopsy and may improve PCa detection.

Comparison of Real-Time Elastography and Multiparametric MRI for Prostate Cancer Detection: A Whole-Mount Step-Section Analysis

“…In contrast, multiparametric MRI reveals structural and tissue perfusion information. The usefulness of combining RTE with contrast-enhanced ultrasound has been found in previous studies [6,22].…”

Real-Time Elastography of the Prostate

“…Because of encouraging technical innovations and developments in prostate imaging, it is now possible to visualise PCa with high sensitivity [7, 8]. Beside PCa localisation, modern imaging modalities are capable of providing information about tumour volume, local staging, and cancer aggressiveness, which may be helpful for choosing the most appropriate therapy [8, 9].…”

“…Beside PCa localisation, modern imaging modalities are capable of providing information about tumour volume, local staging, and cancer aggressiveness, which may be helpful for choosing the most appropriate therapy [8, 9]. …”

Multiparametric Ultrasound of the Prostate: Adding Contrast Enhanced Ultrasound to Real-Time Elastography to Detect Histopathologically Confirmed Cancer

“…Using a multiparametric targeted biopsy approach Aigner et al observed that the overall 59.4% PC detection rate (70 of 133 cases) was superior to that of a systematic approach. 26 Combining RTE and CEUS in our study significantly decreased the false-positive results of RTE alone from 34.9% to 10.3% and thereby improved the positive predictive value to 89.7% to correctly identify histopathologically confirmed PC in defined TLs. Although there was a trend toward higher Gleason patterns in hyperperfused TLs in our study, statistical analysis did not attain significance to assign a Gleason score to a hypoperfused or hyperperfused imaging pattern in our pilot study.…”