Value of EGD in patients referred for cholecystectomy: a systematic review and meta-analysis

Lamberts, Mark P.; Kievit, Wietske; Özdemir, Cihan; Westert, Gert P.; Laarhoven, Cornelis J. H. M. van; Drenth, Joost P.H.

doi:10.1016/j.gie.2015.01.024

Cited by 17 publications

(9 citation statements)

References 25 publications

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“…proven gallbladder sludge with the characteristic biliary pain (29). Routine esophagogastroduodenoscopy is not indicated before elective cholecystectomy (2,4,30). The treatment goals of cholecystectomy are prevention or reduction of renewed biliary pain; avoidance of later and elimination of existing complications of cholelithiasis; and prevention of gallbladder cancer in high-risk patients.…”

Section: Tokyo (7 10 22)mentioning

confidence: 99%

The Treatment of Gallstone Disease

Gutt¹,

Schläfer²,

Lammert³

2020

Deutsches Ärzteblatt International

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Background: Gallstone disease affects up to 20% of the European population, and cholelithiasis is the most common reason for hospitalization in gastroenterology. Methods: This review is based on pertinent publications retrieved by a selective search of the literature, including the German clinical practice guidelines on the diagnosis and treatment of gallstones and corresponding guidelines from abroad. Results: Regular physical activity and an appropriate diet are the most important measures for the prevention of gallstone disease. Transcutaneous ultrasonography is the paramount method of diagnosing gallstones. Endoscopic retrograde cholangiography should only be carried out as part of a planned therapeutic intervention; endosonography beforehand lessens the number of endoscopic retrograde cholangiographies that need to be performed. Cholecystectomy is indicated for patients with symptomatic gallstones or sludge. This should be performed laparoscopically with a four-trocar technique, if possible. Routine perioperative antibiotic prophylaxis is not necessary. Cholecystectomy can be performed in any trimester of pregnancy, if urgently indicated. Acute cholecystitis is an indication for early laparoscopic cholecystectomy within 24 hours of admission to hospital. After successful endoscopic clearance of the biliary pathway, patients who also have cholelithiasis should undergo laparoscopic cholecystectomy within 72 hours. Conclusion: The timing of treatment for gallstone disease is an essential determinant of therapeutic success.

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Section: Tokyo (7 10 22)mentioning

confidence: 99%

The Treatment of Gallstone Disease

Gutt¹,

Schläfer²,

Lammert³

2020

Deutsches Ärzteblatt International

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“…Routine esophago-gastroduodenoscopy (EGD) in patients referred for cholecystectomy is not recommended. Despite the diagnostic sensitivity of endoscopic yield, a meta-analysis of 12 cohort studies comprising 6,317 patients reported that its value as a tool to prevent surgery is limited, hence preoperative EGD should only be considered selectively [344].…”

Section: Preoperative Investigationsmentioning

confidence: 99%

EASL Clinical Practice Guidelines on the prevention, diagnosis and treatment of gallstones

2016

Journal of Hepatology

435

165

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“…Cholecystectomy is the gold standard for the treatment of symptomatic cholelithiasis ( 2 ), and the number of this surgery has also increased significantly. According to the information statistics, there are about 800,000 cases of cholecystectomy in the United States each year, and the number is also increasing in China annually ( 3 , 4 ).…”

Section: Introductionmentioning

confidence: 99%

Bacterial Alterations in Post-Cholecystectomy Patients Are Associated With Colorectal Cancer

Ren

Zhang

et al. 2020

Front. Oncol.

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Background: Although increasing evidences showed a correlation between cholecystectomy and the prevalence rate of colorectal cancer (CRC), and shed light on gut microbiota in colorectal pathogenesis, only a few studies focused on microbial alterations after cholecystectomy, and its sequent role in carcinogenesis and progression of CRC has not been reported. Thus, we aimed to investigate the bacterial alterations and tried to clarify their clinical significance. Methods: 104 subjects were enrolled and divided into post-cholecystectomy patients (PC, n = 52) and healthy controls (HC, n = 52). To investigate the bacterial role in carcinogenesis, PC patients were further separated into preCA_CRC (patients with precancerous lesions and/or CRC, n = 9) and non-CA (patients without precancerous lesions and CRC, n = 43) based on the histopathology. Qualified stool samples were collected for 16S rRNA gene sequencing to analyze the bacterial profile. Results: Our data showed noteworthy compositional and abundant alterations of bacterial microbiota in PC patients, characterized as Bacteroides ovatus, Prevotella copri , and Fusobacterium varium remarkably increased; Faecalibacterium prausnitzii, Roseburia faecis , and Bifidobacterium adolescentis significantly decreased. Additionally, the duration after cholecystectomy was the critical factor that affected bacterial composition. Machine learning-based analysis showed a pivotal role of Megamonas funiformis in discriminating PC from HC subjects and involving in the progression of CRC. Conclusions: The bacterial dysbiosis may associate with CRC in PC patients, and the duration after cholecystectomy was highlighted as an important factor. Altered bacterial microbiota was likely to play a pivotal role in related-disease in the long-term follow-up of PC patients.

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Value of EGD in patients referred for cholecystectomy: a systematic review and meta-analysis

Cited by 17 publications

References 25 publications

The Treatment of Gallstone Disease

The Treatment of Gallstone Disease

EASL Clinical Practice Guidelines on the prevention, diagnosis and treatment of gallstones

Bacterial Alterations in Post-Cholecystectomy Patients Are Associated With Colorectal Cancer

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