Valor pronóstico de las cifras de hemoglobina en el momento del alta en pacientes hospitalizados por insuficiencia cardiaca

Sánchez-Torrijos, Jorge; Gudín-Uriel, Margarita; Nadal-Barangé, Mercedes; Jacas-Osborn, Victoria; Trigo-Bautista, Alberto; Giménez-Alcalá, Mónica; Payá-Serrano, Rafael; Ridocci-Soriano, Francisco

doi:10.1157/13096601

Cited by 11 publications

(1 citation statement)

References 33 publications

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“…[ 6 7 ] It has been shown that anemia has higher prevalence in patients with congestive heart failure, it is associated with rehospitalization due to decompensation and cardiac mortality, and it is related to poorer survival in the short term in cases of acute heart failure. [ 8 9 ] The correlation of mortality in heart failure with renal function, BNP, and ferritin that is an indicator of anemia also suggests the presence of a relationship between renal functions and BNP and ferritin. Thus, in this study, in patients with acute heart failure, we examined the relationship between acute renal injury (ARI) risk and BNP and ferritin, and a third combined parameter, i.e., the ratio of BNP/ferritin, which, to our knowledge, has not been previously investigated in the literature.…”

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confidence: 99%

B-type natriuretic peptide/ferritin ratio as a predictor of the risk of developing acute renal injury in acute decompensated heart failure

et al. 2021

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OBJECTIVES: Acute decompensated heart failure (ADHF) is a clinical condition that requires urgent diagnosis and treatment. Patients present with pulmonary capillary wedge pressure, pulmonary arterial pressure, and venous pressure elevation. Along with the progressive deterioration observed in the clinical picture, impairment or deterioration of kidney function may also occur. In this study, we evaluated the B-type natriuretic peptide (BNP)/ferritin ratio as a predictor of the risk of developing acute renal injury (ARI) in ADHF. METHODS: A total of 157 patients with a diagnosis of ischemic dilated cardiomyopathy for more than 6 months that presented to our clinic with ADHF were included in this cohort study. After the treatment protocol was applied, the sample was divided into two groups as patients with and without ARI. The BNP and ferritin levels were examined along with the routine blood parameters (BNP), and the BNP, ferritin, and BNP/ferritin values were compared between the groups. RESULTS: ARI was present in 34.3% ( n = 54) of the patients, who were also found to have higher BNP (892.76 vs. 817.54), lower ferritin (86.78 ± 57.2 vs. 105.46 ± 38.3), and higher BNP/ferritin (10.48 ± 2.14 vs. 7.89 ± 1.89). The multivariate logistic regression analysis revealed the BNP/ferritin ratio as an independent risk factor for ARI (odds ratio = 3.19; 95% CI, 1.92-6.54; P = 0.001). Using the receiver operating characteristic curve, a cutoff value of 9.32 for BNP/ferritin ratio had a sensitivity of 81.8% and a specificity of 93.5% (area under the curve 0.842, P < 0.001) for the prediction of ARI. CONCLUSION: The BNP/ferritin ratio is a new parameter that can be used to draw attention to the severity of the treatment and renal function in ADHF cases in emergency situations.

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Section: Introductionmentioning

confidence: 99%

B-type natriuretic peptide/ferritin ratio as a predictor of the risk of developing acute renal injury in acute decompensated heart failure

et al. 2021

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The prevalence of anemia in chronic heart failure and its impact on the clinical outcomes

Tang

Katz

2008

Heart Fail Rev

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This review article summarizes the current medical literature reporting on the prevalence and prognostic significance of anemia in patients with heart failure. Almost all currently available data indicate that anemia is common in heart failure populations, with the majority of studies indicating prevalence >20%. Anemia appears to be more highly prevalent in patients with advanced age, with more severe limitations in functional capacity, and with greater severity of co-morbid chronic kidney disease. In most reported studies anemia is an independent predictor of increased mortality risk and increased risk of hospitalization for heart failure. These data provide the rationale for interventional treatment trials to determine if anemia is in the causal pathway for disease progression and increased mortality risk in HF patients.

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OBSOLETE: Anemia in Heart Failure

Patel

Altman²

2018

Reference Module in Biomedical Sciences

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Valor pronóstico de las cifras de hemoglobina en el momento del alta en pacientes hospitalizados por insuficiencia cardiaca

Cited by 11 publications

References 33 publications

B-type natriuretic peptide/ferritin ratio as a predictor of the risk of developing acute renal injury in acute decompensated heart failure

B-type natriuretic peptide/ferritin ratio as a predictor of the risk of developing acute renal injury in acute decompensated heart failure

The prevalence of anemia in chronic heart failure and its impact on the clinical outcomes

OBSOLETE: Anemia in Heart Failure

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