Validity and Reliability of the Neuropsychiatric Inventory Questionnaire Version in Patients With Stroke or Transient Ischemic Attack Having Cognitive Impairment

Choi

Dement Geriatr Cogn Disord Extra

et al. 2016

Aim: This study aims to provide a brief questionnaire form of the Neuropsychiatric Inventory (NPI-Q) in Korean translated from the original NPI-Q that is intended for the evaluation of behavioral and psychological symptoms of dementia in routine clinical practice. Patients and Methods: We developed a Korean version of the NPI-Q (KNPI-Q) and compared subitems with those of the Korean version of the NPI (KNPI) in 63 dementia patients; 47 patients had been diagnosed with Alzheimer's disease with dementia, 8 with vascular dementia, and 8 with dementia with Lewy body disease. The diagnosis was based on the National Institute of Neurological and Communicative Disorders and Stroke - Alzheimer's Disease and Related Disorders Association criteria for possible and probable Alzheimer's disease and the International Statistical Classification of Diseases and Related Health Problems, 10th revision, criteria for vascular dementia and other dementing diseases. All patients received the Korean version of the Mini-Mental State Examination and the Clinical Dementia Rating within 1 month of the KNPI-Q. Results: Test-retest reliability of the KNPI-Q using a Pearson correlation index was r = 0.89 for the total symptom scale and r = 0.90 for the distress scale. The prevalence of analogous symptom ratings differed by less than 6.7%. Convergent validity between the KNPI-Q and the NPI using a Pearson correlation index was r = 0.879 for the total symptom scale and r = 0.92 for the distress scale. Conclusions: The KNPI-Q is a reliable and brief instrument that can be employed for screening in the evaluation of neuropsychiatric symptoms of dementia and associated caregiver distress. It may be suitable for use in general clinical practice and could be administered as a brief neuropsychiatric interview.

Section: Introductionmentioning

confidence: 99%

Validation Study of the Korean Version of the Brief Clinical Form of the Neuropsychiatric Inventory

Choi

Dement Geriatr Cogn Disord Extra

et al. 2016

“…Thus in this study, Chinese version of NPI was used to perform comprehensive evaluation and understanding mental and behavioral symptoms in VaD patients. It is reported that Chinese version of NPI has favourable internal validity in Chinese and the consistency of Chinese version of NPI in Chinese is relatively high [14,15]. The correlations of mental and behavioral symptoms in VaD patients with cognitive impairment, education status, age and other factors were further analysed.…”

Section: Discussionmentioning

confidence: 99%

Analysis of Related Factors of Behavioral and Psychiatric Symptoms in Vascular Dementia

Chen¹,

Pan²,

Kong³

2015

J Psychiatry

Journal of Psychiatry AbstractObjective: The aims of this study were to investigate the relationship between behavioral and psychological symptoms and cognitive disturbances, ages, educations of patients and investigate the correlations among Neuropsychiatric inventory (NPI) items in patients with vascular dementia (VaD).Methods: NPI and Mini-Mental State Examination (MMSE) were used to assess the behavioral and psychological symptoms in 120 cases with VaD and 61 cases healthy elders as control group. Results:The score about delusion, hallucination, agitation, dysphoria, apathy, irritability, aberrant motor and appetite/eating change in the NPI list were significantly increased compared with control group (P<0.05), in which the highest score in turn were dysphoria, apathy and irritability. Among the 8 items in the NPI list, delusion, apathy and aberrant motor were significantly corelated with cognitive disorder (P<0.05), and abnormal behavior was corelated with ages and educations. Besides, NPI factors analysis showed there were three behavioral sub-syndromes, such as psychosis, mood disorder and behavioral disturbance. Conclusions:Behavioral and psychological symptoms were common in VaD patients, and the frequency and severity of behavioral and psychological symptoms were corelated with cognitive disturbances, ages, and education status at different degrees.

“…The 12-item scale is used to assess the behaviour of PwD across 12 domains of commonly displayed BPSD. The scale has been translated into >40 languages, has been cross-validated against the NPI as the gold standard (r=0.73) and has demonstrated good validity (sensitivity=74.1%, specificity=79.5%), internal reliability (α=0.783) and excellent test–retest reliability (r=0.99) 27 28. Total severity scores range from 0 to 36; higher values are indicative of higher severity.…”

Section: Methods and Analysismentioning

confidence: 99%

HOMESIDE: home-based family caregiver-delivered music and reading interventions for people living with dementia: protocol of a randomised controlled trial

et al. 2019

IntroductionPharmacological interventions to address behavioural and psychological symptoms of dementia (BPSD) can have undesirable side effects, therefore non-pharmacological approaches to managing symptoms may be preferable. Past studies show that music therapy can reduce BPSD, and other studies have explored how formal caregivers use music in their caring roles. However, no randomised study has examined the effects on BPSD of music interventions delivered by informal caregivers (CGs) in the home setting. Our project aims to address the need for improved informal care by training cohabiting family CGs to implement music interventions that target BPSD, and the quality of life (QoL) and well-being of people with dementia (PwD) and CGs.Methods and analysisA large international three-arm parallel-group randomised controlled trial will recruit a sample of 495 dyads from Australia, Germany, UK, Poland and Norway. Dyads will be randomised equally to standard care (SC), a home-based music programme plus SC, or a home-based reading programme plus SC for 12 weeks. The primary outcome is BPSD of PwD (measured using the Neuropsychiatric Inventory-Questionnaire). Secondary outcomes will examine relationship quality between CG and PwD, depression, resilience, competence, QoL for CG and QoL for PwD. Outcomes will be collected at baseline, at the end of the 12-week intervention and at 6 months post randomisation. Resource Utilisation in Dementia will be used to collect economic data across the life of the intervention and at 6-month follow-up. We hypothesise that the music programme plus SC will generate better results than SC alone (primary comparison) and the reading programme plus SC (secondary comparison).Ethics and disseminationEthical approval has been obtained for all countries. Results will be presented at national and international conferences and published in scientific journals and disseminated to consumer and caregiver representatives and the community.Trial registration numbersACTRN12618001799246p; NCT03907748