Validation of the Women’s Health Initiative Insomnia Rating Scale in a Multicenter Controlled Clinical Trial

Levine, Douglas W.; Dailey, Margaret E.; Rockhill, Beverly; Tipping, Diane; Naughton, Michelle J.; Shumaker, Sally A.

doi:10.1097/01.psy.0000151743.58067.f0

Cited by 88 publications

(82 citation statements)

References 48 publications

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“…In addition, while the literature on risk factors for insomnia in breast cancer remains relatively new [4], there are data suggesting the importance of vasomotor symptoms vis-a`-vis insomnia in studies of breast cancer [8,54] and menopausal women in general [38][39][40][41][42][43]. Vasomotor symptoms are well-established sequelae of the climacteric, whether natural or treatment induced.…”

Section: Discussionmentioning

confidence: 99%

“…While other cut-points on the WHI-IRS can be used, Levine et al recommend a score of 9 to minimize false-positives while maintaining acceptable sensitivity [62]. The WHI-IRS was validated in 66 269 postmenopausal women [61] and a clinical trial involving 850 postmenopausal women [40]. The WHI-IRS has a stable factor structure [61]; excellent internal consistency (Cronbach's α = 0.79 in our data set and in the validation study [62]) and test-retest (r = 0.84 for 8−14 days) reliability [62]; and, validity [41,62].…”

Section: Sleep Assessmentmentioning

confidence: 99%

“…low physical activity [15,23,24], alcohol intake [25,26], smoking [27][28][29][30][31]), poor physical health [32,33] and physical symptoms (e.g. pain [23,[34][35][36][37], vasomotor symptoms [38][39][40][41][42][43]), and poor psychosocial functioning (e.g. poor social functioning [44,45], life stress [15,[46][47][48][49], depression/depressive symptoms [19,23,50], and personality traits such as anger/hostility [51]).…”

Section: Introductionmentioning

confidence: 99%

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The relative importance of specific risk factors for insomnia in women treated for early‐stage breast cancer

et al. 2007

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Section: Discussionmentioning

confidence: 99%

Section: Sleep Assessmentmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The relative importance of specific risk factors for insomnia in women treated for early‐stage breast cancer

et al. 2007

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“…In the current study, the internal reliability of the depression and anxiety subscale were α=.87 and α=.83 respectively. The Women's Health Initiative Insomnia Rating Scale (WHIIRS) (Levine et al, 2005) was used to assess sleep disturbances, and was administered at follow-up. The WHIIRS consists of five items, four of these items are related either to initiation insomnia, maintenance insomnia, or early morning awakening and the last item is related to sleep quality.…”

Section: Methodsmentioning

confidence: 99%

The association among depressive symptoms, smoking status and antidepressant use in cardiac outpatients

et al. 2009

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Both depression and smoking are highly prevalent and related to poorer outcomes in cardiac patients. In this study, the authors examined the association between depressive symptoms and smoking status, described the frequency and type of antidepressant use, and prospectively tested the effects of antidepressant use in smokers on smoking status and psychosocial outcomes. Participants comprised 1498 coronary artery disease (CAD) outpatients who completed a baseline survey which assessed depressive symptoms, current medications, and smoking status. A second survey was mailed 9 months later that assessed depressive symptoms, anxiety, insomnia, current medications and smoking status. Results showed that current and former-smokers had significantly greater depressive symptoms than non-smokers. Ten percent of patients were taking antidepressants, most frequently SSRIs, with significantly more smokers on antidepressants than former and non-smokers. At follow-up, smokers on antidepressants were less likely to have quit, had greater anxiety, depressive symptoms and insomnia than smokers not using antidepressants. This study demonstrated that smokers and quitters with CAD had greater depressive symptoms and use of antidepressants than non-smokers, but that the antidepressants utilized may not be optimizing outcomes.

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“…Diversos instrumentos/ questionários têm sido utilizados para a caracterização dos sintomas de insônia em mulheres na peri e na pós-menopausa e para a avaliação de mudanças em resposta à terapêutica hormonal. Entre esses instrumentos, destaca-se a escala de insônia do Women's Health Initiative Study (WHI), validada e utilizada em dois estudos de mulheres em pós-menopausa que apresentavam calores noturnos e insônia e que receberam tratamento com estrógenos ou placebo (Levine et al;. Outro instrumento validado é o questionário de qualidade de vida específico para a menopausa ou Menopause-Specific Quality of Life Questionnaire (MEN-QOL).…”

Section: Sintomas Vasomotores E Insônia Na Menopausaunclassified

Insônia na menopausa e perimenopausa: características clínicas e opções terapêuticas

Soares¹

2006

Rev. psiquiatr. clín.

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Revisão de LiteraturaInsônia na menopausa e perimenopausa -características clínicas e opções terapêuticas CLAUDIO N. SOARES 1 ResumoTranstornos do sono e insônia são mais freqüentemente observados entre as mulheres do que entre os homens durante a vida adulta. Entre outros fatores, especula-se que alta comorbidade psiquiátrica para transtornos afetivos e ansiosos entre as mulheres contribua para maior ocorrên-cia de insônia. Além disso, períodos de intensa variabilidade hormonal (por exemplo, gestação e puerpério, perimenopausa) parecem estar relacionados com maior incidência de insônia e de transtornos respiratórios do sono entre as mulheres. Estudos populacionais sugerem que a transição menopausal constitue um período de maior risco para o desenvolvimento de sintomas depressivos, vasomotores e de insônia. Este artigo examina os fatores clínicos e hormonais que contribuem para a ocorrência de insônia durante a peri e a pós-menopausa. Opções terapêuticas são discutidas, incluindo técnicas cognitivo-comportamentais, tratamentos hormonais, agentes hipnótico-sedativos, antidepressivos e tratamentos de medicina alternativa.Palavras-chave: Insônia, mulheres, menopausa, hipnóticos, estrógenos. AbstractSleep disturbances and insomnia are more commonly observed in adult females than in adult males. It has been speculated that comorbid depression and anxiety among females may contribute to a higher incidence of insomnia. In addition, periods of intense hormonal variability (e.g.; pregnancy/postpartum, menopause transition) appear to be associated with higher incidence of sleep disturbances in females. Epidemiologic studies suggest that the menopausal transition constitutes a period of heightened risk for the occurrence of depressive symptoms and vasomotor complaints, as well as insomnia. This article reviews the clinical and hormone factors that may play a role for the development of insomnia during the menopausal transition and postmenopause. Treatment options are critically reviewed, including cognitive-behavioral techniques, hormonal treatments, hypnotics, antidepressants, and complimentary/alternative medicine.

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Validation of the Women’s Health Initiative Insomnia Rating Scale in a Multicenter Controlled Clinical Trial

Abstract: The construct validity of the WHIIRS was supported because it was successfully used to detect self-reported sleep disturbance differences in women taking HT versus those taking a placebo as well as in groups known to differ in severity of their vasomotor symptoms.

Cited by 88 publications

References 48 publications

The relative importance of specific risk factors for insomnia in women treated for early‐stage breast cancer

The relative importance of specific risk factors for insomnia in women treated for early‐stage breast cancer

The association among depressive symptoms, smoking status and antidepressant use in cardiac outpatients

Insônia na menopausa e perimenopausa: características clínicas e opções terapêuticas

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