Validation of the International Prostate Symptom Score in Chinese males and females with lower urinary tract symptoms

Abstract

ObjectivesTo evaluate the translation of the IPSS (Hong Kong Chinese version 1) and to assess the applicability, validity, reliability and sensitivity of the instrument in both males and females with LUTS in Chinese population.MethodsThe translation of the IPSS (Hong Kong Chinese version 1) was reviewed through back translation. Modifications were made, resulting in the development of The IPSS (Hong Kong Chinese version 2). The content validity was assessed by contend validity index. 233 subjects with LUTS were recruited in Hong Kong primary care settings for pilot psychometric testing. The construct validity was assessed by corrected item-total correlation and Pearson’s correlation test against ICIQ-UI SF, IIQ-7 and SF-12 v2. The reliability was assessed by the internal consistency (Cronbach’s Alpha coefficient) and test –retest reliability (Intraclass correlation coefficient). The Sensitivity was determined by performing known group comparisons by independent T-test.ResultsThe content validity index for all items could reach 1. Corrected item-total correlation scores were ≥0.4 for four symptom questions (feeling of incomplete bladder emptying, intermittency, weak stream and straining). Overall, the total symptom score moderately correlated with ICIQ-UI SF. The quality of life score moderately correlated with the IIQ-7 but weakly correlated with SF-12 v2. Overall, the reliability of the IPSS (Hong Kong Chinese version 2) was acceptable (Cronbach’s Alpha coefficient = 0.71, ICC of the symptom questions =0.8, ICC of the quality of life question =0.7). The symptoms questions and quality of life questions of the IPSS (Hong Kong Chinese versions 2) were sensitive in detecting differences between groups.ConclusionsThe IPSS (Hong Kong Chinese version 2) is a valid, reliable and sensitive measure to assess Chinese females and males with lower urinary tract symptoms. The IPSS quality of life question is more sensitive than the generic quality of life measure to differentiate subgroups.

Patient-reported health outcomes in long-term lung transplantation survivors: A prospective cohort study

“…However, both genders showed significant improvement in HRQoL afterward. The worse HRQoL among females was predominantly in the physical domains of the NHP, concurring with findings for both healthy people and populations with chronic lung diseases in previous studies 21, 29, 30, 31, 32, 33. According to those studies, this difference in HRQoL is not related to the difference in the severity of the symptoms between males and females.…”

The Modified Urdu version of International Prostate Symptom Score: A psychometric validation study

“…The overall (both males and females) internal consistency of IPSS-U was satisfactory and comparable to the original English IPSS. Similar to the findings of an earlier study, [6] the Cronbach's alpha was slightly lower in females (0.66), which is still acceptable. The two week test-retest reliability in individuals with no change in their complaints from the baseline was excellent and comparable to the other versions of IPSS.…”

“…The two week test-retest reliability in individuals with no change in their complaints from the baseline was excellent and comparable to the other versions of IPSS. [6][7][8][9][10][11][12] As expected, factor analysis yielded two independent factors in our IPSS modified for Urduspeaking people. Incomplete bladder emptying, intermittency, poor stream and straining were components of the first factor (Voiding symptoms), whereas frequency, urgency to urinate and nocturia storage symptoms were components of the second factor.…”

“…The IPSS has been translated and validated in many languages of the world. [6][7][8][9][10][11] However, it has not been translated and validated in Urdu language which is a national language of Pakistan, and being spoken in several Asian countries. Therefore, the Urdu version of IPSS may not only be useful in assessing the severity of LUTS in Urdu speaking patients and guiding patient management but it is also an important research tool.…”

“…Although IPSS was originally designed to assess benign prostatic hyperplasia-related LUTS, it is widely used and acknowledged as a validated, non-disease specific and non-sex specific questionnaire. [3][4][5][6] IPSS is an 8-item questionnaire (7-items to assess LUTS and one QOL question). The first seven items assess the frequency and severity of urinary symptoms; incomplete bladder emptying, frequency of urination, intermittency, urgency to urinate, poor urinary stream, straining and nocturia.…”