Validation of the German version of the Chronic Liver Disease Questionnaire

Haüser, Winfried; Schnur, Martina; Steder-Neukamm, Ulf; Muthny, F. A.; Grandt, Daniel

doi:10.1097/00042737-200406000-00014

Cited by 59 publications

(74 citation statements)

References 21 publications

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“…Figure 1 compares the distribution of the Chinese (HK) CLDQ scores with those from other countries. The distribution pattern of the Chinese (HK) CLDQ subscale scores was very similar to those of other countries [3,9,11,13] , except Italy, supporting cross-cultural conceptual equivalence. Table 3 shows the mean item scores and standard deviation of the 29 CLDQ items grouped under their hypothesized subscales.…”

Section: Subjectsmentioning

confidence: 65%

“…Previous studies showed that the CLDQ is more responsive than a generic measure to detect a change in patients with CLD [3,9] . It has been translated and validated in different languages [9][10][11][12][13] , supporting its potential for crosscultural adaptation. However, most of the psychometric data of the CLDQ have been derived from patients with hepatitis C virus (HCV) infection and Western populations.…”

Section: Introductionmentioning

confidence: 99%

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Psychometrics of the chronic liver disease questionnaire for Southern Chinese patients with chronic hepatitis B virus infection

Lam¹,

Lam²,

Lai³

et al. 2009

WJG

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AIM:To test the psychometric properties of a Chinese [(Hong Kong) HK] translation of the chronic liver disease questionnaire (CLDQ). METHODS:A Chinese (HK) translation of the CLDQ was developed by iterative translation and cognitive debriefing. It was then administered to 72 uncom plicated and 78 complicated chronic hepatitis B (CHB) patients in Hong Kong together with a structured questionnaire on service utilization, and the Chinese (HK) SF36 Health Survey Version 2 (SF36v2). RESULTS:Scaling success was ≥ 80% for all but three items. A new factor assessing sleep was found and items of two (Fatigue and Systemic Symptoms) subscales tended to load on the same factor. Internal consistency and testretest reliabilities ranged from 0.580.90 for different subscales. Construct validity was confirmed by the expected correlations between the SF36v2 Health Survey and CLDQ scores. Mean scores of CLDQ were significantly lower in complicated compared with uncomplicated CHB, supporting sensitivity in detecting differences between groups. CONCLUSION:The Chinese (HK) CLDQ is valid, reliable and sensitive for patients with CHB. Some modifi cations to the scaling structure might further improve its psychometric properties.

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Section: Subjectsmentioning

confidence: 65%

Section: Introductionmentioning

confidence: 99%

Psychometrics of the chronic liver disease questionnaire for Southern Chinese patients with chronic hepatitis B virus infection

Lam¹,

Lam²,

Lai³

et al. 2009

WJG

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“…Качество жизни (КЖ) оценивали по опрос-нику для пациентов с ХЗП -CLDQ (The chronic liver disease questionnaire) [10,24].…”

Section: дизайн исследованияunclassified

“…Ответ респондентов включает 7 возможных вариантов: от «постоянно» до «никогда». Чем выше суммарный показатель опросника, тем более высокий уровень КЖ у пациента [10,24]. Достоверное улучшение КЖ получено в группе пациентов на комбинированной схеме лекарственных средств.…”

Section: результаты исследования и обсуждениеunclassified

Experience of Ornithine Aspartate (Hepa-Merz) and Probiotics Bioflorum Forte in the Treatment of Non-Severe Forms of Alcoholic and Non-Alcoholic Fatty Liver Disease

Ильченко

Мельникова

Журавлева

2016

Arhivʺ vnutrennej mediciny

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“…[4][5][6] It has been translated and validated into various languages all over the world including both European (German, 7 Spanish, 8 Italian, 9 Swedish,…”

Section: Introductionmentioning

confidence: 99%

Translation and validation of the Hindi version of chronic liver disease questionnaire (CLDQ) for the assessment of health related quality of life in patient with chronic liver disease in India

Benjamin¹,

Mani²,

Saraya³

et al. 2016

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Background: Chronic liver disease questionnaire (CLDQ) is an established disease specific tool to assess the health related quality of life (HRQOL) in patients with CLD irrespective of the etiology and severity. The objective of the study was to develop the Hindi language version of CLDQ and to assess the validity of the Hindi CLDQ. Methods: CLDQ was adapted into Hindi language by following a standard method of forward and back-translation by two bilingual translators, revision by expert panel and formulation of a consensual version followed by pilot testing and appropriate modifications before final administration. Hindi CLDQ along with short form 36 (SF-36) were administered in 494 patients with chronic liver disease (CLD) and 103 healthy controls (HC). To assess reproducibility, Hindi CLDQ was re-administered in a subsample of 20 patients. Internal consistency was assessed by Cronbach's alpha coefficient. Structural validity was assessed by exploratory factor analysis and construct validity was assessed with help of correlation of SF-36 scores and CLDQ pattern across disease severity groups. Results: The Cronbach's alpha coefficient was 0.93 and intra class coefficient correlation was 0.88 for the average CLDQ score, suggestive of good reliability. An inverse relationship of the average CLDQ score with the disease severity (CLDQ score of Child A vs. B vs. C = 5.2±1.10 vs. 4.73±1.24 vs. 4.15±1.19 respectively; p<0.001) and good correlation with SF-36 scores (average CLDQ score with PCS & MCS; r=0.63 & 0.55; p<0.001) was suggestive of good validity of Hindi CLDQ. The factor analysis identified 6 domains accounting for 62% of variability. The derived cut-off of 6 for the average CLDQ had the AUC of 0.826 with a sensitivity of 82.6 and a specificity of 76.7. Conclusion: Hindi version of CLDQ is found to be a reliable and a valid tool comparable to the original English version. The HRQOL of patients with CLD is lower than healthy controls and HRQOL decreases with increase in disease severity.

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Validation of the German version of the Chronic Liver Disease Questionnaire

Abstract: The CLDQ-D is well accepted by patients with chronic liver diseases and has good reliability and satisfactory discriminant validity.

Cited by 59 publications

References 21 publications

Psychometrics of the chronic liver disease questionnaire for Southern Chinese patients with chronic hepatitis B virus infection

Psychometrics of the chronic liver disease questionnaire for Southern Chinese patients with chronic hepatitis B virus infection

Experience of Ornithine Aspartate (Hepa-Merz) and Probiotics Bioflorum Forte in the Treatment of Non-Severe Forms of Alcoholic and Non-Alcoholic Fatty Liver Disease

Translation and validation of the Hindi version of chronic liver disease questionnaire (CLDQ) for the assessment of health related quality of life in patient with chronic liver disease in India

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