Validation of the Chinese version of Addenbrooke's Cognitive Examination III for diagnosing dementia

Wang, Bian-Rong; Ou, Zhou; Gu, Xiang; Wei, Chenchen; Xu, Jun; Shi, Jian-Quan

doi:10.1002/gps.4680

Cited by 35 publications

(53 citation statements)

References 22 publications

(35 reference statements)

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“…A maximum score of 100 can be obtained, with higher scores indicating better cognitive performance. ACE-III has recently been developed and validated in English (Hsieh et al, 2013), Egyptian-Arabic (Qassem et al, 2015), Spanish (Matías-Guiu et al, 2016), Thai (Charernboon et al, 2016), and Chinese (Wang et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

Italian version and normative data of Addenbrooke's Cognitive Examination III

Pigliautile

Chiesi

Stablum

et al. 2018

Int. Psychogeriatr.

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Section: Introductionmentioning

confidence: 99%

Italian version and normative data of Addenbrooke's Cognitive Examination III

Pigliautile

Chiesi

Stablum

et al. 2018

Int. Psychogeriatr.

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“…Such a trend was also evident in other studies. 20,26,48 Another similar study 49 showed that in a younger age group (60-69 years) with higher educational attainment (>10 years of schooling), the majority of the population scored above 80 on the ACE-III. In contrast, a completely opposite trend was seen with the cut-off value below 80.…”

Section: Discussionmentioning

confidence: 95%

“…Similar findings were reported in other languages as well. 26,43 In addition, the subdomains of ACE-III cover more cognitive abilities than the HMSE, which makes it more advantageous in detecting underlying cognitive difficulties in dementia and its other subtypes, such as frontotemporal dementia. The high sensitivity and specificity obtained in the present study and other studies 19,26 further reinforce its usefulness.…”

Section: Dovepressmentioning

confidence: 99%

“…21 Moreover, ACE-III has also been validated in other conditions, such as brain injury, stroke, and Parkinsonism, 18,22 yielding excellent diagnostic utility and helping clinicians to make more precise decisions about cognitive impairment and dementia. Several studies 24,25 have shown that the cut-off values of ACE-III are influenced by sociodemographic variables, such as age, 26 education, 20 and language. 27 Such factors play an important role when interpreting the suggested cut-off values as they affect the diagnostic accuracy in diverse populations.…”

Section: Introductionmentioning

confidence: 99%

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<p>Hindi Version of Addenbrooke’s Cognitive Examination III: Distinguishing Cognitive Impairment Among Older Indians at the Lower Cut-Offs</p>

Bajpai¹,

Upadhyay²,

Sati³

et al. 2020

CIA

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Background: Screening and diagnostic tests provide an objective measure of cognitive performance and also aid in distinguishing mild cognitive impairment (MCI) from major neurocognitive disorder (MNCD). Further, when such tests are culturally and educationally unbiased, it strengthens their diagnostic utility. This study aimed to validate the Hindi version of Addenbrooke's Cognitive Examination III (ACE-III) in Indian older adults and compare its validity with the Hindi Mini-Mental State Examination (HMSE). Methods: A sample of 412 consenting older adults visiting a memory clinic was recruited into the study. They were categorized into three groups: healthy controls (n=222), MCI (n=70), and MNCD (n=120). The complete clinical protocol was followed. Hindi ACE-III and HMSE were administered and were statistically analyzed. Results: The optimal cutoff values to detect MCI and MNCD with ACE-III were 71 and 62 (AUC: 0.849 and 0.884), respectively, which were slightly higher than with HMSE (AUC: 0.822, 0.861). Education-and age-stratified cutoffs were also computed. Conclusion: Hindi ACE-III has good discriminating power at lower cutoffs than the standard scores in differentiating between MCI and MNCD.

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“…Matias-Guiu et al ( 2017 ) reported that ACE-III is a useful test for assessing memory, language, attention, and visuospatial function, in addition to early Alzheimer's disease. In another study, Wang et al ( 2017 ) reported that the Chinese version of ACE-III is a reliable assessment tool for comparing cognition with the mini-mental state examination (MMSE). The MoCA is specifically used in mild cognitive impairment (MCI) screening, and total MoCA scores have been shown to correlate with MMSE scores (Nasreddine et al, 2005 ).…”

Section: Discussionmentioning

confidence: 99%

A Clinical Research Study of Cognitive Dysfunction and Affective Impairment after Isolated Brainstem Stroke

Wang

et al. 2017

Front. Aging Neurosci.

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Although the function of the cerebellum in neurocognition has been well-documented, the similar role of the brainstem has yet to be fully elucidated. This clinical research study aimed to combine data relating to neuropsychological assessments and P300 to explore cognitive dysfunction and affective impairment following brainstem stroke. Thirty-four patients with isolated brainstem stroke and twenty-six healthy controls were recruited; for each patient, we collated data pertaining to the P300, Addenbrooke's Cognitive Examination III (ACE-III), Montreal Cognitive Assessment Chinese version (MoCA), trail-making test (TMT), Symbol Digit Modalities Test (SDMT), Wechsler Adult Intelligence Scale-Digit Spans (DS), Stroop test, Self Rating Depression Scale (SDS), and Self Rating Anxiety Scale (SAS). Significance was analyzed using an independent T-test or the Mann-Whitney U-test. Correlation was analyzed using Pearson's correlation analysis or Spearman's correlation analysis. Collectively, data revealed that brainstem stroke caused mild cognitive impairment (MCI), and that visuospatial, attention, linguistic, and emotional disturbances may occur after isolated brainstem stroke. Cognitive decline was linked to P300 latency, ACE-III, and MoCA; P300 latency was correlated with ACE-III. Patients with right brainstem lesions were more likely to suffer memory decline. The present study provides initial data relating to the role of the brainstem in neurocognition, and will be useful for further understanding of vascular cognitive and affective impairment.

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Validation of the Chinese version of Addenbrooke's Cognitive Examination III for diagnosing dementia

Abstract: The present findings support that the Chinese version of ACE-III is a reliable assessment tool for dementia. Copyright © 2017 John Wiley & Sons, Ltd.

Cited by 35 publications

References 22 publications

Italian version and normative data of Addenbrooke's Cognitive Examination III

Italian version and normative data of Addenbrooke's Cognitive Examination III

<p>Hindi Version of Addenbrooke’s Cognitive Examination III: Distinguishing Cognitive Impairment Among Older Indians at the Lower Cut-Offs</p>

A Clinical Research Study of Cognitive Dysfunction and Affective Impairment after Isolated Brainstem Stroke

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