Purpose: To adapt a magnetization-prepared spiral imaging technique, termed T1prep, for time-efficient radiofrequency (RF)-insensitive prostate T 1 quantification at 1.5 T and evaluate signal-to-noise ratio (SNR) limits to voxelbased versus subregion analysis.
Materials and Methods:A magnetization-prepared spiral imaging technique was adapted for robust T 1 contrast development, multislice imaging within 5 minutes, and data regression to a monoexponential decay. In vitro testing evaluated RF insensitivity of the multislice acquisition plus method accuracy. A pilot study was performed in 15 patients with low or intermediate risk localized prostate cancer.