Validation of questionnaire‐based long‐term dietary exposure to polychlorinated biphenyls using biomarkers

Abstract

FFQ-based PCB exposure estimates show acceptable validity in relation to PCB concentrations in serum, justifying their use in large-scale epidemiological studies.

Dietary exposure to polychlorinated biphenyls and risk of myocardial infarction — A population-based prospective cohort study

“…In particular fatty fish from contaminated waters can contain high levels of PCBs. The major dietary sources of PCB exposure are fish (67%), dairy products (19%) and meat products (9%) [25]. The content of PCB and MeHg in foods was obtained from the Swedish National Food Agency and the Swedish Environmental Protection Agency's monitoring programs [32].…”

“…The PCBdatabase, described in detail elsewhere, [25] was based on concentrations of PCB congener 153 present in food at the time of baseline. PCB congener 153 is the most abundant congener in food on the Swedish market and the level of PCB 153 is an excellent indicator for total PCB levels in food as well as in human blood serum [22,[29][30][31].…”

“…eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) ascribed cardiovascular benefits [26,27]. The aim of the present study was to assess the association between validated estimates of dietary PCB exposure [25] and risk of myocardial infarction in a population-based prospective cohort study of middle-aged and elderly women, taking into account the intake of EPA and DHA.…”

“…PCBs accumulate and magnify in the food chain where fatty fish is the main contributor to dietary PCB exposure in populations with relatively high fish consumption [24,25]. Fish is also the main source of intake of long-chain omega-3 fatty acids, i.e.…”

China action of “Cleanup Plan for Polychlorinated Biphenyls Burial Sites”: Emissions during excavation and thermal desorption of a capacitor-burial site

“…More concernedly, PCBs are potential carcinogens (Ruder et al, 2013). Despite the fact that exposure to high levels of PCBs is rare, long-term exposure to low levels may cause chronic health effects because PCBs easily accumulate in fatty tissues via food consumptions (Bergkvist et al, 2012). There have undoubtedly been a series of international agreements made toward reducing and controlling PCBs to enter the environment (Dyke et al, 2003;Kalinovich et al, 2008).…”