Validation of optical properties quantification with a dual-step technique for biological tissue analysis

Sorgato, Verónica; Berger, Michel; Emain, Charlotte; Vever‐Bizet, Christine; Dinten, Jean‐Marc; Bourg-Heckly, Geneviève; Planat-Chrétien, Anne

doi:10.1117/1.jbo.23.9.096002

Cited by 6 publications

(3 citation statements)

References 23 publications

(40 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Therefore, to estimate DeACs, insufficient information is available, leading to large error. Prior information from a different imaging modality can be used to decrease DeAC estimation error [30,87,88]. Because of the use of US transducers in PA data collection, US-PA dual modality is a natural choice to obtain such prior information.…”

Section: Discussionmentioning

confidence: 99%

Quantitative Photoacoustic Tomography Using Iteratively Refined Wavefield Reconstruction Inversion: A Simulation Study

Ranjbaran,

Aghamiry,

Gholami

et al. 2024

IEEE Trans. Med. Imaging

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Quantitative Photoacoustic Tomography Using Iteratively Refined Wavefield Reconstruction Inversion: A Simulation Study

Ranjbaran,

Aghamiry,

Gholami

et al. 2024

IEEE Trans. Med. Imaging

View full text Add to dashboard Cite

“…At the same time, due to the availability of materials, ease of preparation, and ethical significance, gelatin is increasingly replacing natural biological tissues for research applications [ 4 , 5 ] in medical engineering, including forensic and military wound profiling and projectile damage simulation objects [ 6 , 7 ], medical phantom materials in imaging [ 8 , 9 ], tissue regeneration materials [ 10 , 11 ], and tissue substitutes in surgical simulations [ 12 ]. However, previous research has focused on the application of gelatin in high-speed projectile damage simulation [ 13 ].…”

Section: Introductionmentioning

confidence: 99%

Study on the Similarity of Biomechanical Behavior between Gelatin and Porcine Liver

Zhao

Cao

et al. 2020

BioMed Research International

View full text Add to dashboard Cite

As a natural polymer, gelatin is increasingly being used as a substitute for animals or humans for the simulation and testing of surgical procedures. In the current study, the similarity verification was neglected and a 10 wt.% or 20 wt.% gelatin sample was used directly. To compare the mechanical similarities between gelatin and biological tissues, different concentrations of gelatin samples were subjected to tensile, compression, and indentation tests and compared with porcine liver tissue. The loading rate in the three tests fully considered the surgical application conditions; notably, a loading speed up to 12 mm/s was applied in the indentation testing, the tensile test was performed at a speed of 1 mm/s until fracture, and the compression tests were compressed at a rate of 0.16 mm/s and 1 mm/s. A comparison of the results shows that the mechanical behaviors of low-concentration gelatin samples involved in the study are similar to the mechanical behavior of porcine liver tissue. The results of the gelatin material were mathematically expressed by the Mooney-Rivlin model and the Prony series. The results show that the material properties of gelatin can mimic the range of mechanical characteristics of porcine liver, and gelatin can be used as a matrix to further improve the similarity between substitute materials and biological tissues.

show abstract

“…Due to the availability of materials, ease of preparation, and ethical significance, gelatin is increasingly replacing natural biological tissues for research applications [1], [2] in medical engineering, including forensic and military wound profiling, projectile damage simulation [3], [4], as medical phantom materials in imaging [5], [6], tissue regeneration materials [7], [8], and tissue substitutes in surgical simulations [9]; however, previous research has focused on the damage behaviour of gelatin under high-speed rigid impact. The impact velocity of a high-speed waterjet exceeds that under rigid separation, and the functional characteristics thereof are unclear.…”

Section: Introductionmentioning

confidence: 99%

Separation Behaviour Difference Between Gelatin and Porcine Liver Under High-Speed Waterjet Impact

Cao

Zhao

et al. 2019

IEEE Access

View full text Add to dashboard Cite

Different from the rigid separation of biological tissue by scalpel, medical waterjet technology utilizes the impact kinetic energy of high-speed waterjet to instantly destroy the surface of biological tissue to achieve better clinical separation effect. Since the gelatin samples are transparent biomaterials, they were taken as the only substitute for soft tissue in experimental studies and observation in the current studies of medical waterjet separation technology, but the mechanical behavioural difference between the two has not been reported. To verify the adaptability of gelatin as a substitute of soft tissue under the impact of high-speed waterjet. Firstly, the dynamic process of impact was described through the energy balance equation. Then, based on the principle of altering a single variable, the difference of damage depth between 8 wt. %, 10 wt. %, and 12 wt. % gelatin samples and porcine liver tissue under various impact pressure, impact distance, and waterjet speed of motion (as opposed to flow velocity) was compared. The results show that the gelatin sample replicates the damage behaviour of porcine liver samples under the specific waterjet impact conditions, and the direction of the waterjet hydraulic power optimisation of the two materials is also consistent: however, due to the different sampling sites and anisotropy of porcine liver samples, the mechanical response of soft tissue under high-speed waterjet impact cannot be fully expressed by gelatin samples. The experimental results can provide support for the further study of medical waterjet separation technology.INDEX TERMS High-speed impact, medical waterjet, separation behavior, surgical instruments, tissue engineering.

show abstract

Validation of optical properties quantification with a dual-step technique for biological tissue analysis

Cited by 6 publications

References 23 publications

Quantitative Photoacoustic Tomography Using Iteratively Refined Wavefield Reconstruction Inversion: A Simulation Study

Quantitative Photoacoustic Tomography Using Iteratively Refined Wavefield Reconstruction Inversion: A Simulation Study

Study on the Similarity of Biomechanical Behavior between Gelatin and Porcine Liver

Separation Behaviour Difference Between Gelatin and Porcine Liver Under High-Speed Waterjet Impact

Contact Info

Product

Resources

About