Eur. J. Chem. volume 4, issue 1, P58-60 2013 DOI: 10.5155/eurjchem.4.1.58-60.678
Tadjuddin Naid, Wahyu Rizandi Syukur, Amran Ilyas, Seniwati Dali, Baharuddin Hamzah

KEYWORDSThe study was conducted with the purpose to develop and validate a high performance liquid chromatography method with UV detector to determine ketoprofen content in tablet preparation using ethanol-phosphate buffer (pH = 6.0, 80:20, v:v). The method was validated toward parameters of accuracy, precision, linearity, selectivity, LOD and LOQ. The results obtained fulfill the validation requirement of the ketoprofen tablet in the form of LOD = 0.5302 ppm and LOQ = 1.7676 ppm.


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