Computational phylogenetics is in the process of revolutionizing historical linguistics. Recent applications have shed new light on controversial issues, such as the location and time depth of language families and the dynamics of their spread. So far, these approaches have been limited to single-language families because they rely on a large body of expert cognacy judgments or grammatical classifications, which is currently unavailable for most language families. The present study pursues a different approach. Starting from raw phonetic transcription of core vocabulary items from very diverse languages, it applies weighted string alignment to track both phonetic and lexical change. Applied to a collection of ∼1,000 Eurasian languages and dialects, this method, combined with phylogenetic inference, leads to a classification in excellent agreement with established findings of historical linguistics. Furthermore, it provides strong statistical support for several putative macrofamilies contested in current historical linguistics. In particular, there is a solid signal for the Nostratic/Eurasiatic macrofamily. The scope of this method, according to a near-consensus in the field, is intrinsically limited to a time depth of ∼10,000 y, however. Over the past century, there have been an abundance of proposals for macrofamilies going back further in time. Few of these proposals are currently backed up by evidence as strong as is required by the professional standards of historical comparative linguistic research. These professional standards demand reconstruction of a substantial portion of the protolanguage's vocabulary and grammar plus the historic processes leading to its attested descendants, which are vetted and approved by the scholarly community via peer review. So far, Afro-Asiatic is arguably the only macrofamily coming close to meeting these criteria; all other proposals along those lines are currently hypotheses at best, with varying degree of empirical justification. Perhaps the most intensely discussed such proposal concerns the Eurasiatic macrofamily (2, 3), comprising a large portion of uncontroversial families from Eurasia. A recent statistical study by Pagel et al. (4) estimated its time depth at 14,450 y.The study by Pagel et al. (4), as well as other recent applications of phylogenetic methods to historical linguistics (5-7) (for critical assessments see refs. 8 and 9), bases its inference on expert cognacy judgments. These judgments are largely consensual within accepted language families but necessarily controversial beyond that limit. Therefore, the findings of Pagel et al. (4) have sparked a fair amount of critical discussion among historical linguists (e.g., 10). Grammatical classifications (11,12) are an alternative to cognacy data; they are also available only on a relatively small sample of languages in sufficient detail at this time.To sidestep this issue, the present investigation pursues a purely data-oriented approach not reliant on expert judgments. It is based on data from the Automated ...