Abstract:Sensitive, simple and specific spectrophotometric and spectrofluorimetric methods were developed for the determination of triamterene in bulk powder and pharmaceutical dosage form. The spectrophotometric method (Method A) is based on the formation of an ion‐pair complex with eosin Y in acetate buffered solution of pH 3.7 followed by measuring the absorbance at 545 nm. The absorbance–concentration plot is rectilinear over the range 3.0–15.0 μg/mL with a limit of detection (LOD) of 0.429 μg/mL and a limit of qua… Show more
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