Validasi Kriteria Diagnosis Infeksi Saluran Kemih Berdasarkan American Academy of Pediatrics 2011 pada Anak Usia 2-24 Bulan

Trinadi, Ikhsan; Arguni, Eggi; Hermawan, Kristia

doi:10.14238/sp18.1.2016.17-20

Cited by 2 publications

(2 citation statements)

References 8 publications

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“…Hal yang sama juga diungkapkan oleh Tullus dan Shaikh 9 yaitu spesifisitas pemeriksaan nitrit urin ini sangat tinggi untuk mendiagnosis ISK, namun sensitivitasnya hanya sekitar 50%, dan pemeriksaan nitrit pada bayi dan anak-anak tidak cocok karena cenderung sering berkemih. Trinadi et al 20 16 dengan jumlah sampel sebanyak 10.258 anak, mendapatkan 1007 anak (98,2%) positif nitrit, tetapi hanya 617 anak (6,1%) yang positif kultur urin.…”

Section: Nitrit Positifunclassified

Perbandingan Leukosituria, Nitrit, Leukosit Esterase dengan Kultur Urin dalam Mendiagnosis Infeksi Saluran Kemih pada Anak

Sabriani¹,

Umboh²,

Manoppo³

2021

MSJ

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Urinary tract infection (UTI) in children is the most common infection after upper airway infection. The diagnosis of UTI is based on urine culture, however, this examination takes a longer time and is quite expensive. Therefore, the diagnosis of UTI can also be confirmed by using leukocyturia, nitrite, and leukocyte esterase tests although they can not replace urine culture as the gold standard. This study was aimed to determine the accuracy of positive leukocyturia, positive nitrite, positive leukocyte esterase examination, combination of positive leukocyturia and nitrite examinations, positive leukocyturia and leukocyte esterase, and leukocyturia, nitrite, positive leukocyte esterase in diagnosing UTI. This was a literature review study. The results of the literature review showed that the range of accuracy of UTI diagnosis using positive leukocyte esterase examinations was 9-6.8%, positive nitrite was 2.8-100%, leukocyte esterase was 13.7-86%, combination of positive leukocyturia and nitrite had a sensitivity value of 33 %, and specificity of 94%, combination of positive leukocytic and leukocytic esterase had a sensitivity value of 70% and a specificity of 90%, and combination of leukocyturia, nitrite, and leukocyte esterase had an accuracy range of 100%. In conclusion, these examinations coul be used to confirm the diagnosis of UTI in children especially if the urine culture can not be performed on them.Keywords: urinary tract infection (UTI), leukocyturia, nitrite, leukocyte esterase, urine culture, children Abstrak: Infeksi saluran kemih (ISK) merupakan infeksi yang paling sering terjadi pada anak setelah infeksi saluran napas atas. Diagnosis ISK ditegakkan berdasarkan hasil pemeriksaan kultur urin, namun pemeriksaan ini membutuhkan waktu yang lama dan biaya yang cukup mahal. Pemeriksaan leukosituria, nitrit, dan leukosit esterase juga membantu dalam mendiagnosis ISK, namun ketiga pemeriksaan ini belum dapat menggantikan kultur urin sebagai baku emas untuk mendiagnosis ISK. Penelitian ini bertujuan untuk mengetahui seberapa besar ketepatan pemeriksaan leukosituria positif, nitrit positif, leukosit esterase positif, gabungan pemeriksaan leukosituria dan nitrit positif, leukosituria dan leukosit esterase positif, dan gabungan leukosituria, nitrit, leukosit esterase positif dalam mendiagnosis ISK. Jenis penelitian ialah literature review. Hasil penelitian menunjukkan kisaran ketepatan diagnosis ISK menggunakan pemeriksaan leukosituria positif yaitu 9-6,8%, nitrit positif sebesar 2,8-100%, leukosit esterase sebesar 13,7-86%, gabungan leukosituria dan nitrit positif memiliki nilai sensitivitas 33%, dan spesifisitas sebesar 94%, gabungan leukosituria dan leukosit esterase positif memiliki nilai sensitivitas 70% dan spesifisitas sebesar 90%, serta gabungan pemeriksaan leukosituria, nitrit, dan leukosit esterase memiliki kisaran ketepatan sebesar 100%. Simpulan penelitian ini ialah pemeriksan-pemeriksaan tersebut dapat membantu menegakkan diagnosis ISK pada anak terutama bila kultur urin tidak memungkinkan dilakukan.Kata kunci: infeksi saluran kemih (ISK), leukosituria, nitrit, leukosit esterase, kultur urin, anak

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Section: Nitrit Positifunclassified

Perbandingan Leukosituria, Nitrit, Leukosit Esterase dengan Kultur Urin dalam Mendiagnosis Infeksi Saluran Kemih pada Anak

Sabriani¹,

Umboh²,

Manoppo³

2021

MSJ

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“…Urine nitrite examination is used to determine bacteriuria, because nitrite is the result of nitrate metabolism which is reduced by bacteria that have reductase enzymes such as bacteria in the Enterobactericeae group . Nitrite has a specificity of 98% and a sensitivity of 53% for diagnosing UTI (Trinadi et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Correlation of Leukocyte Esterase Positivity Levels Against the Results of Several Examination Parameters Laboratory Urinary Tract Infection in Patients at Mataram City Regional Hospital

Waisnawa,

Wiadnya,

Manu

et al. 2023

JAMBS

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Background : Urinary tract infection (UTI) is caused by the multiplication of bacteria in the urinary tract. The standard proving procedures for UTI are urine culture examination and urine dipstick examination (leukocyte esterase and nitrite). Objective : This study aims to measure leukocyte and nitrite values, calculate the total number of bacteria, identify Gram type, species and antibiotic sensitivity and analyze the correlation of leukocyte esterase positivity to the results of several UTI examination parameters. Research Methods : The method used is an analytic observational design with cross sectional design using primary data and analyzed with the Spearman rank test. Results : The results showed that in 198 patients with suspected UTI, 123 (62%) were positive for leukocyte esterase, 16 (8.1%) were positive for nitrite. The total number of bacterial countshowed 82 people (41%) with bacteriuria ≥10 5 CFU/mL. Found 61 Gram-negative bacilli and 21 Gram-positive cocci with 21 different bacterial species. Antibiotic sensitivity test showed 51% sensitive, 6% intermediate and 43% resistant. Correlation of leukocyte esterase with nitrites (p 0.023<0.05), total bacteria count (p 0.00<0.05), Gram negative bacilli (p 0.00<0.05), and Gram positive cocci (p 0.533>0.05), antibiotic sensitivity test (p 0.794 >0.05) and bacterial species (p 0.316>0.05). Conclusion : The results showed that there was a correlation between the level of positivity of leukocyte esterase and nitrite, total bacteria count and Gram-negative bacilli, but there was no correlation between Gram-positive cocci, bacterial species and antibiotic sensitivity tests.

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Validasi Kriteria Diagnosis Infeksi Saluran Kemih Berdasarkan American Academy of Pediatrics 2011 pada Anak Usia 2-24 Bulan

Cited by 2 publications

References 8 publications

Perbandingan Leukosituria, Nitrit, Leukosit Esterase dengan Kultur Urin dalam Mendiagnosis Infeksi Saluran Kemih pada Anak

Perbandingan Leukosituria, Nitrit, Leukosit Esterase dengan Kultur Urin dalam Mendiagnosis Infeksi Saluran Kemih pada Anak

Correlation of Leukocyte Esterase Positivity Levels Against the Results of Several Examination Parameters Laboratory Urinary Tract Infection in Patients at Mataram City Regional Hospital

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