Vacuum-assisted closure therapy and wound coverage in soft tissue injury

Abstract

This study presents the results of a meta-analysis based on the literature dealing with the clinical applications of vacuum-assisted closure (VAC) in the areas of chronic wounds, acute posttraumatic wounds, compartment syndromes, or injuries of the upper extremities. The studies were analysed for validity, significance of conclusion with respect to success rate, publications, and economic efficacy. The data show that with VAC a very valuable technique has been added to an integrated therapeutic concept of soft tissue reconstruction. However, clinical data from prospective randomised trials to support some of the positive aspects seen in the daily clinical application of the technique are still missing. These would create a sound basis demonstrating the economic efficacy of the technique.

Illustrated operative management of spontaneous bleeding and compartment syndrome of the lower extremity in a patient with acquired hemophilia A: a case report

“…As summarized by Holle et al . [32], it functions by stabilizing tissue, giving protection against infections, improving blood circulation within tissues, and induction of wound healing. McCallon et al .…”

Cost analysis of Topical Negative Pressure (TNP) Therapy for traumatic acquired wounds

“…Trueman et al [11] already showed a significant reduction in hospitalization time with a standardization of TNP-therapy. But until now, there exist no standardized guidelines for the use of TNP therapy [4], [19]. …”

Gastrointestinal fistula endoscopic closure techniques

“…Weidenhagen et al described the use of EVAC in 2003 for the management of anastomotic leaks after rectal surgery [ 61 ]. A later systematic review of 17 colorectal studies showed an average healing rate of 85% after a median follow up of 47 days [ 62 ].…”