Introduction. Ecthyma gangrenosum is a rare skin disorder which commonly
affects immunocompromised patients. Case Report. We report two hematological
patients suffering from ecthyma gangrenosum. Pseudomonas aeruginosa was
isolated from skin lesions of both patients, but bacteremia was present only
in the first case. These two cases had different pathogenic mechanisms and
outcomes. Conclusion. Early diagnosis and prompt combination antibiotic
therapy are of utmost importance in the treatment of this condition. On the
other hand, the underlying disease has a great impact on the outcome as
well.