Vaccination and Reduced Severity of COVID-19 Pneumonia Viewed at Chest Radiography

Borghesi, Andrea; Maroldi, Roberto

doi:10.1148/radiol.220309

Cited by 3 publications

(2 citation statements)

References 5 publications

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“…One of the recent studies observed this only in univariate analyses, while multivariate logistic regression did not demonstrate this [ 23 ]. In studies with a higher rate of vaccinated patients (53.1%), Brixia score was higher in the unvaccinated COVID-19 patients (median, 5; interquartile range [IQR], 3–7) compared to the vaccinated ones (median, 1; IQR, 0–6) ( p < 0.001), while normal CXR was found in 13% of the unvaccinated group and 36% of the vaccinated ( p < 0.001) [ 24 ]. Others have presented that patients who were fully vaccinated had lower risk of admission into intensive care units (OR, 0.08 [95% CI: 0.09, 0.78; p = 0.02]) [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

Brixia Chest X-ray Score, Laboratory Parameters and Vaccination Status for Prediction of Mortality in COVID-19 Hospitalized Patients

Nukovic,

Opancina,

Zdravkovic

et al. 2023

Diagnostics

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Chest X-ray has verified its role as a crucial tool in COVID-19 assessment due to its practicability, especially in emergency units, and Brixia score has proven as a useful tool for COVID-19 pneumonia grading. The aim of our study was to investigate correlations between main laboratory parameters, vaccination status, and Brixia score, as well as to confirm if Brixia score is a significant independent predictor of unfavorable outcome (death) in COVID-19 patients. The study was designed as a cross-sectional multicentric study. It included patients with a diagnosed COVID-19 infection who were hospitalized. This study included a total of 279 patients with a median age of 62 years. The only significant predictor of unfavorable outcome (death) was Brixia score (adjusted odds ratio 1.148, p = 0.022). In addition, the results of the multiple linear regression analysis (R2 = 0.334, F = 19.424, p < 0.001) have shown that male gender (B = 0.903, p = 0.046), severe COVID-19 (B = 1.970, p < 0.001), and lactate dehydrogenase (B = 0.002, p < 0.001) were significant positive predictors, while albumin level (B = −0.211, p < 0.001) was a significant negative predictor of Brixia score. Our results provide important information about factors influencing Brixia score and its usefulness in predicting the unfavorable outcome (death) of COVID-19 patients. These findings have clinical relevance, especially in epidemic circumstances.

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Section: Discussionmentioning

confidence: 99%

Brixia Chest X-ray Score, Laboratory Parameters and Vaccination Status for Prediction of Mortality in COVID-19 Hospitalized Patients

Nukovic,

Opancina,

Zdravkovic

et al. 2023

Diagnostics

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“…Fortunately, following the massive introduction of COVID-19 vaccination programs in European countries—on 1 October 2023, the total number of vaccine doses administered in Europe was 1,736,552,311 [ 4 ]—the severity of the disease has significantly decreased, and the situation is gradually returning to normalcy [ 5 , 6 , 7 , 8 ]. Specifically, the WHO declared on 5 May 2023 that the global emergency caused by SARS-CoV-2 was over—and we hope it will be forever.…”

Section: Introductionmentioning

confidence: 99%

Residual Lung Abnormalities in Survivors of Severe or Critical COVID-19 at One-Year Follow-Up Computed Tomography: A Narrative Review Comparing the European and East Asian Experiences

Borghesi,

Ciolli,

Antonelli

et al. 2023

Tomography

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The literature reports that there was a significant difference in the medical impact of the coronavirus disease (COVID-19) pandemic between European and East Asian countries; specifically, the mortality rate of COVID-19 in Europe was significantly higher than that in East Asia. Considering such a difference, our narrative review aimed to compare the prevalence and characteristics of residual lung abnormalities at one-year follow-up computed tomography (CT) after severe or critical COVID-19 in survivors of European and East Asian countries. A literature search was performed to identify articles focusing on the prevalence and characteristics of CT lung abnormalities in survivors of severe or critical COVID-19. Database analysis identified 16 research articles, 9 from Europe and 7 from East Asia (all from China). Our analysis found a higher prevalence of CT lung abnormalities in European than in Chinese studies (82% vs. 52%). While the most prevalent lung abnormalities in Chinese studies were ground-glass opacities (35%), the most prevalent lung abnormalities in European studies were linear (59%) and reticular opacities (55%), followed by bronchiectasis (46%). Although our findings required confirmation, the higher prevalence and severity of lung abnormalities in European than in Chinese survivors of COVID-19 may reflect a greater architectural distortion due to a more severe lung damage.

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Duration and severity of COVID‐19 symptoms among primary healthcare workers: A cross‐sectional survey

Ma,

Lu,

Zhang

et al. 2024

Journal of Advanced Nursing

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AimsThis study aims to investigate the epidemiological characteristics of COVID‐19 infection among healthcare workers, including the severity, duration of infection, post‐infection symptoms and related influencing factors.MethodsA self‐administered questionnaire was utilized to assess the post‐infection status of primary healthcare workers in Jiangsu Province. The questionnaire collected information on demographic characteristics, lifestyle habits, post‐infection clinical manifestations, work environment and recovery time of the respondents. Customized outcome events were selected as dependent variables and logistic regression models were employed to analyse the risk factors. Phi‐coefficient was used to describe the relationship between post‐infection symptoms.ResultsThe analysis revealed that several factors, such as female, older age, obesity, previous medical history, exposure to high‐risk environments and stress, were associated with a higher likelihood of experiencing more severe outcomes. On the other hand, vaccination and regular exercise were found to contribute to an earlier resolution of the infection. Among the post‐infection symptoms, cough, malaise and muscle aches were the most frequently reported. Overall, there was a weak association among symptoms persisting beyond 14 days, with only cough and malaise, malaise and dizziness and headache showing a stronger correlation.ConclusionThe study findings indicate that the overall severity of the first wave of infection, following the complete lifting of restrictions in China, was low. The impact on primary healthcare workers was limited, and the post‐infection symptoms exhibited similarity to those observed in other countries. It is important to highlight that these conclusions are specifically relevant to the population infected with the Omicron variant.ImpactsThis study helps to grasp the impacts of the first wave of COVID‐19 infections on healthcare workers in China after the national lockdown was lifted.PatientsPrimary healthcare workers in Jiangsu Province, including doctors, nurses, pharmacists and other personnel from primary healthcare units such as community health service centres and health centres.

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Vaccination and Reduced Severity of COVID-19 Pneumonia Viewed at Chest Radiography

Cited by 3 publications

References 5 publications

Brixia Chest X-ray Score, Laboratory Parameters and Vaccination Status for Prediction of Mortality in COVID-19 Hospitalized Patients

Brixia Chest X-ray Score, Laboratory Parameters and Vaccination Status for Prediction of Mortality in COVID-19 Hospitalized Patients

Residual Lung Abnormalities in Survivors of Severe or Critical COVID-19 at One-Year Follow-Up Computed Tomography: A Narrative Review Comparing the European and East Asian Experiences

Duration and severity of COVID‐19 symptoms among primary healthcare workers: A cross‐sectional survey

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