Brixia Chest X-ray Score, Laboratory Parameters and Vaccination Status for Prediction of Mortality in COVID-19 Hospitalized Patients

Abstract

Chest X-ray has verified its role as a crucial tool in COVID-19 assessment due to its practicability, especially in emergency units, and Brixia score has proven as a useful tool for COVID-19 pneumonia grading. The aim of our study was to investigate correlations between main laboratory parameters, vaccination status, and Brixia score, as well as to confirm if Brixia score is a significant independent predictor of unfavorable outcome (death) in COVID-19 patients. The study was designed as a cross-sectional multicentric study. It included patients with a diagnosed COVID-19 infection who were hospitalized. This study included a total of 279 patients with a median age of 62 years. The only significant predictor of unfavorable outcome (death) was Brixia score (adjusted odds ratio 1.148, p = 0.022). In addition, the results of the multiple linear regression analysis (R2 = 0.334, F = 19.424, p < 0.001) have shown that male gender (B = 0.903, p = 0.046), severe COVID-19 (B = 1.970, p < 0.001), and lactate dehydrogenase (B = 0.002, p < 0.001) were significant positive predictors, while albumin level (B = −0.211, p < 0.001) was a significant negative predictor of Brixia score. Our results provide important information about factors influencing Brixia score and its usefulness in predicting the unfavorable outcome (death) of COVID-19 patients. These findings have clinical relevance, especially in epidemic circumstances.

The Impact of COVID-19 on the Tuberculosis Features in a Romanian Pneumology Hospital

“…Extent of lung parenchyma damage evaluation by BRIXIA score, consists of division into six sections of the lung radiologic image, in which each section achieves a damage score of 0, 1, 2 or 3, while total score could sum from 0 to 18. 20–22 …”

“…Extent of lung parenchyma damage evaluation by BRIXIA score, consists of division into six sections of the lung radiologic image, in which each section achieves a damage score of 0, 1, 2 or 3, while total score could sum from 0 to 18. [20][21][22] The inclusion criteria were age over 20 years, signing the informed consent for the use of personal data for the purpose of medical statistical studies, according to the standardized form from the clinical observation sheet.…”

The Impact of COVID-19 on the Tuberculosis Outcomes in a Pneumology Hospital from South-East Romania

“…The BRIXIA radiological scores for severity were evaluated on the date of COVID-19 diagnosis (baseline) and at discharge (end of study). Extent of lung parenchyma damage evaluation by BRIXIA score, consists of division into six sections of the lung radiologic image, in which each section achieve a score of 0, 1, 2 or 3, while total score could sum from 0 to 18 [15][16][17].…”