This paper proposes simulation of non-ionizing electromagnetic radiation effect of Action Potential (AP) signal in the electrical nerve fiber of the human arm model by using the Computer Simulation Technology (CST) software. In this case, the primary challenge to model the human bodies and tissues and to simulate the propagation and introduce radiation of an implanted antenna from inside the human bodies. Thus, the main contribution of this work is the AP signal has been created with different antenna positions in the homogeneous human arm flat and cylindrical shape model using Ultra Wideband (UWB) coplanar stripline-fed antenna. The design of UWB antenna is based on Computer Simulation Technology (CST) software and Poly (methyl methacrylate) (PMMA) substrate, which operated from 3.1 GHz to 10.6 GHz. The process of AP signal creation including the consideration of the human arm model in the complete electrical circuit system based on the schematic circuit of the nervous system and implementing of Izhikevcih's MATLAB programming. The simulated antenna manages to realize 10.71 GHz bandwidth at two resonance frequencies, 5.27 GHz and 9.45 GHz. Overall, the proposed system offers the AP signal analysis with difference antenna position in the multilayer human arm model and the significant effect of radiation is in the cylindrical shape model.