Uveo-meningeal Syndromes

Ray, Robin; Foroozan, Rod

doi:10.1097/iio.0b013e3181572281

Cited by 4 publications

(1 citation statement)

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“…Potential bacterial causes include Bartonella , tuberculosis, syphilis, Lyme disease and Whipple disease. Fungi such as Candida albicans and Aspergillus are also potential causes, as are viruses like herpes simplex, varicella-zoster and cytomegalovirus [ 3 ] . In our case, all CSF, blood cultures and serologies were negative.…”

Section: Discussionmentioning

confidence: 99%

Uveo-Meningitis and Myelodysplastic Syndrome

Ferrão

Ribeirinho-Soares

Almeida

2022

European Journal of Case Reports in Internal Medicine

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Uveo-meningeal syndromes are any disorder characterized by the involvement of the uvea and the meninges. They can have multiple causes, including infectious, autoimmune and malignant diseases. We report the case of a patient with a 10-year-old diagnosis of myelodysplastic syndrome that had been stable. He presented with new onset uveitis, ataxia, diplopia and fluctuating consciousness level, without any obvious cause revealed by brain imaging or blood chemistries. An extensive aetiological search showed no obvious cause. Initially, the patient improved spontaneously and was discharged. However, 2 months later, he deteriorated once again, this time with disperse adenomegalies that were not present previously. The bone marrow biopsy showed a high number of blasts, which affirmed the progression of the previously known myelodysplastic syndrome. The lymph nodes were not biopsied due to very low life expectancy, making the procedure futile. A presumptive diagnosis of uveo-meningitis caused by paraneoplastic syndrome was made. The patient died a few months later.

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Section: Discussionmentioning

confidence: 99%