UVB phototherapy and photochemotherapy (PUVA) in the treatment of polymorphic light eruption and solar urticaria

Addo, H.A.; Sharma, Surabhi

doi:10.1111/j.1365-2133.1987.tb05875.x

Cited by 85 publications

(51 citation statements)

References 20 publications

(3 reference statements)

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“…Photochemotherapy with PUVA has been successfully employed in the treatment of solar urticaria [12][13][14][15]. The mechanism by which PUVA therapy exerts a beneficial ef fect in solar urticaria may be complex.…”

Section: Discussionmentioning

confidence: 99%

Detection of Action, Inhibition and Augmentation Spectra in Solar Urticaria

Miyauchi

Horio²

1995

Dermatology

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Background: The action spectrum of solar urticaria varies among cases. In addition, light spectra outside the activating wavelengths can influence the wheal formation in selected patients. Objective: To know the mechanisms of light energy, we examined the effect of wavelengths on the skin and the serum factor. Methods: The patient’s skin and serum were exposed to artificial light sources, in vivo and in vitro, respectively. Results: The action spectrum ranged from UVA to visible light (∼480 nm). The exposure to longer wavelengths immediately after the exposure inhibited the development of urticaria. Conversely, the irradiation of longer wavelengths before exposure increased the wheal formation. Furthermore, UVB irradiation prior to the exposure of urticaria-eliciting light also increased the urticarial reaction, while postirradiation of UVB had no effect. The patient developed an urticarial wheal at the site of injection of her own serum, which had been previously exposed to the action spectrum in vitro. Preirradiation increased the production of the photosensitizer, while postirradiation revealed no effect. Ultrafiltration techniques showed that the molecular weight of the photosensitizer is more than 300 kD. Conclusion: We detected action, inhibition and augmentation spectra in a patient with a severe solar urticaria. Various wavelengths influence the wheal-forming factor in complex interactions.

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Section: Discussionmentioning

confidence: 99%

Detection of Action, Inhibition and Augmentation Spectra in Solar Urticaria

Miyauchi

Horio²

1995

Dermatology

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“…13 This protective effect of UVB hardening is often maintained during the summer months, without severe adverse effects. 15,17 It is our policy to maintain regular exposure to small doses of UVB throughout the year. Patients with LE are often photosensitive to UVR and sometimes even to visible light.…”

Section: Discussionmentioning

confidence: 99%

“…[13][14][15][16][17] Various forms of photohardening, such as UVB, both broadband and narrowband; psoralen plus UVA therapy; and a combination of UVA/UVB radiation, have been administered. [14][15][16][17][18] Treatment for these dermatoses is often provided in early spring for a limited period of time.…”

mentioning

confidence: 99%

UV hardening therapy: A novel intervention in patients with photosensitive cutaneous lupus erythematosus

Sanders¹,

Lam²,

Bruijnzeel-Koomen³

et al. 2006

Journal of the American Academy of Dermatology

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“…In this case, it demonstrated an unusual, nonclassifiable porphyrin disturbance. The often satisfying treatment of UV desensitization in solar urticaria [3] seems to have limited value in this case.…”

Section: Discussionmentioning

confidence: 99%