UV-Visible spectroscopic and DFT studies of the binding of ciprofloxacin hydrochloride antibiotic drug with metal ions at numerous temperatures

Trace Detection of Ciprofloxacin in Milk by Label-Free Raman Enhancement using Two-Dimensional Magnesiochromite

“…With an increasing concentration of CFX, the intensity of both peaks increases, as shown in Figure a. The intensity of the absorption peak is enhanced as the metal ions of the material bind effectively with the carboxylate ions and 4-keto oxygen ions of quinolones of CFX by the electrostatic force of attraction and the metal–ligand charge transfer occurs. , In Figure b,c, we present the change in absorbance with varying concentrations of CFX of wavelength ∼280 and 216 nm, respectively. The inset picture present in Figure c is the digital image of liquid exfoliated 2D-MgCr 2 O 4 .…”

“…In Figure a, the 2D material exhibits a sharp absorption peak at 216 nm owing to the charge transfer bands of Cr 3+ in spinel oxide . Upon interaction with varying concentrations of CFX, a new absorption peak at 280 nm has evolved, evidencing the association of the CFX with the 2D-MgCr 2 O 4 . , Figure S1 displays the absorbance spectrum of CFX alone in order to demonstrate that the 280 nm peak is caused by the presence of CFX. The influence of the changing concentration of CFX can be observed by adding 60, 80, 100, 200, and 300 ng/mL concentrations of CFX consecutively.…”

“…In Figure b, the Raman spectra have been plotted when the 2D-MgCr 2 O 4 has interacted with the CFX@milk, i.e., 2D-CFX-milk. In this interaction, the oxygen atoms present on the surface of the material rapidly connect with the positively charged Nitrogen atoms of the piperazinyl ring and the positively charged metal ions of the atomically thin layered material bonded with the carboxylate atoms and 4-keto oxygen ions of the CFX, which boosts the CFX peak noticeably at 1395 cm –1 , 1535 cm –1 , and 748 cm –1 . , Due to the interaction of CFX with the fatty acids present in milk the actual CFX peak which is observed at 1380 cm –1 in water has been shifted toward higher frequency, i.e., at 1395 cm –1 . An elaborate peak assignment of Raman spectra of the 2D-CFX-milk sample is tabulated in Table S2 in the Supporting Information document.…”

“…This material possesses a large number of surface oxygen ions as well as transition metal ions such as Cr 3+ and biocompatible metal ions like Mg 2+ . These properties increase the likelihood of effective binding with CFX to a considerable extent . Moreover, its exceptional thermal stability, convenient accessibility, and remarkable scalability render it highly suitable for sensing applications.…”

Effect of intra-cyclohexane rings in H-shaped reactive molecules on the negative dispersion of optical retardation

“…19 All DFT and time-dependent DFT (TD-DFT) calculations were conducted with the Gaussian16 module. 20,21 In the process of geometry optimization of molecules, dispersion forces were corrected through the Grimme's DFT-D3 scheme. 22 During the optimization process, the major axis of both H-shaped and linear mesogens was aligned along the x -axis of cartesian coordinates in the system.…”