“…Moreover, Kandiah et al [101] have shown that clotting activities in dRVVT and KCT could be separated by polyacrylamide-immobilized PS but not by CL liposomes. In addition, Pengo et al [102] have demonstrated that purified anti-2-GPI display LA activity prolonging dRVVT only in the presence of PLs, and they proposed to perform dRVVT with and without PLs to identify specific antibodies populations with LA activity. On the other hand, it has been shown that purified anti-II from different patients show different reactivity on dRVVT or KCT: some anti-II prolong mainly dRVVT and some anti-2-GPI KCT [103].…”