“…In recent years, hydroxyapatite has attracted interest for use in bone grafting because of their osteoconductive and bioactive properties [10,11]. Other medical applications of hydroxyapatite have also been studied because hydroxyapatite is biocompatible, bioactive, non-toxic, non-inflammatory and non-immunogenic [12,13]. Natural hydroxyapatite bioceramics have recently been extracted from various bio-waste, including corals [14,15], cuttlefish shells [16], porcine teeth and bones, and bovine bones [12,13].…”